HCSGD entry for CA12
1. General information
| Official gene symbol | CA12 |
|---|---|
| Entrez ID | 771 |
| Gene full name | carbonic anhydrase XII |
| Other gene symbols | CAXII HsT18816 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004089 | Carbonate dehydratase activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006730 | One-carbon metabolic process | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0015701 | Bicarbonate transport | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1547324342 | 0.0086402264 | 0.7822116123 | 0.1853458843 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.8810248097 |
| GSE13712_SHEAR | Down | -0.2952131739 |
| GSE13712_STATIC | Down | -0.1898178922 |
| GSE19018 | Up | 0.1053770338 |
| GSE19899_A1 | Up | 0.1169243745 |
| GSE19899_A2 | Up | 0.3894443866 |
| PubMed_21979375_A1 | Down | -0.8563639586 |
| PubMed_21979375_A2 | Down | -0.7832610625 |
| GSE35957 | Up | 0.3797279750 |
| GSE36640 | Down | -1.9936389527 |
| GSE54402 | Down | -0.0433667025 |
| GSE9593 | Up | 1.1535375824 |
| GSE43922 | Down | -1.0293619756 |
| GSE24585 | Down | -1.4467796370 |
| GSE37065 | Up | 0.8729397823 |
| GSE28863_A1 | Up | 0.6823378535 |
| GSE28863_A2 | Up | 0.9419411065 |
| GSE28863_A3 | Down | -0.5064320345 |
| GSE28863_A4 | Down | -0.0842148975 |
| GSE48662 | Down | -0.2544477788 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Hydroflumethiazide | DB00774 | APRD01020 |
| Zonisamide | DB00909 | APRD00004 |
| Hydrochlorothiazide | DB00999 | APRD00092 |
| Ellagic Acid | DB08846 | DB08468 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001475 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT001475 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018561 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022970 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027182 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT031348 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032380 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
