HCSGD entry for CA9
1. General information
| Official gene symbol | CA9 |
|---|---|
| Entrez ID | 768 |
| Gene full name | carbonic anhydrase IX |
| Other gene symbols | CAIX MN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002009 | Morphogenesis of an epithelium | IEA | biological_process |
| GO:0004089 | Carbonate dehydratase activity | IEA | molecular_function |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0006730 | One-carbon metabolic process | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0015701 | Bicarbonate transport | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016323 | Basolateral plasma membrane | IEA | cellular_component |
| GO:0031528 | Microvillus membrane | IEA | cellular_component |
| GO:0033574 | Response to testosterone | IEA | biological_process |
| GO:0042493 | Response to drug | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046903 | Secretion | IEA | biological_process |
| GO:0061418 | Regulation of transcription from RNA polymerase II promoter in response to hypoxia | TAS | biological_process |
| GO:0071456 | Cellular response to hypoxia | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7563070020 | 0.1696999354 | 0.9999902473 | 0.7970385905 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1340452831 |
| GSE13712_SHEAR | Down | -0.2544905704 |
| GSE13712_STATIC | Down | -0.0201423316 |
| GSE19018 | Up | 0.0823755843 |
| GSE19899_A1 | Up | 0.0642619512 |
| GSE19899_A2 | Up | 0.1163328427 |
| PubMed_21979375_A1 | Up | 0.1467093378 |
| PubMed_21979375_A2 | Down | -0.0521672424 |
| GSE35957 | Down | -0.4452295244 |
| GSE36640 | Down | -2.3300178802 |
| GSE54402 | Down | -0.2013260877 |
| GSE9593 | Down | -0.2530382032 |
| GSE43922 | Up | 0.0513962979 |
| GSE24585 | Down | -0.0518459596 |
| GSE37065 | Down | -0.0414180807 |
| GSE28863_A1 | Down | -0.0638087808 |
| GSE28863_A2 | Down | -0.0180934461 |
| GSE28863_A3 | Up | 0.3697863329 |
| GSE28863_A4 | Down | -0.0215830952 |
| GSE48662 | Down | -0.0388077582 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Hydroflumethiazide | DB00774 | APRD01020 |
| Zonisamide | DB00909 | APRD00004 |
| Hydrochlorothiazide | DB00999 | APRD00092 |
| WX-G250 | DB05304 | - |
| Ellagic Acid | DB08846 | DB08468 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027439 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028954 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
