HCSGD entry for CA8


1. General information

Official gene symbolCA8
Entrez ID767
Gene full namecarbonic anhydrase VIII
Other gene symbolsCA-VIII CALS CAMRQ3 CARP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004089Carbonate dehydratase activityIEAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0006730One-carbon metabolic processIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0048015Phosphatidylinositol-mediated signalingIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87665701910.22131071390.99999024730.9050323132

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0325496638
GSE13712_SHEARDown-0.8435298199
GSE13712_STATICDown-0.0477485556
GSE19018Up0.2161803154
GSE19899_A1Up0.1071359691
GSE19899_A2Up0.1720955174
PubMed_21979375_A1Up0.1741290378
PubMed_21979375_A2Up0.0630655921
GSE35957Up0.1228017626
GSE36640Up0.0313775707
GSE54402Down-0.0210897711
GSE9593Down-0.0339063000
GSE43922Up0.0194680428
GSE24585Down-0.7591865554
GSE37065Down-0.1543268967
GSE28863_A1Down-0.0947876112
GSE28863_A2Down-0.1827364402
GSE28863_A3Up0.1534905894
GSE28863_A4Down-0.0054310393
GSE48662Down-0.0627368136

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

ZonisamideDB00909 APRD00004

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024700MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026126MicroarrayFunctional MTI (Weak)19074876
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.