HCSGD entry for ZNF14


1. General information

Official gene symbolZNF14
Entrez ID7561
Gene full namezinc finger protein 14
Other gene symbolsGIOT-4 KOX6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.40841727900.24098809700.99999024730.9452116490

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3373103031
GSE13712_SHEARDown-0.5501101642
GSE13712_STATICDown-0.6636325182
GSE19018Down-0.1883626816
GSE19899_A1Up0.0342288808
GSE19899_A2Up0.1744426264
PubMed_21979375_A1Up1.1515891204
PubMed_21979375_A2Up0.0008493322
GSE35957Down-0.4107724589
GSE36640Down-0.0984950517
GSE54402Down-0.0436651999
GSE9593Down-0.0814316989
GSE43922Up0.0956268927
GSE24585Down-0.1777294817
GSE37065Up0.0400774968
GSE28863_A1Up0.5331772384
GSE28863_A2Up0.2801972470
GSE28863_A3Down-0.0869516586
GSE28863_A4Down-0.0402771415
GSE48662Down-0.3181378214

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

24496748Additionally, expression analysis identified PLEC, C8orf48, TRPC4, and ZNF14, as differentially regulated genes in senescent hMSCs that were similarly regulated in those hMSCs which failed to produce a therapeutic effect in a GVHD trial
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