HCSGD entry for YWHAG
1. General information
| Official gene symbol | YWHAG |
|---|---|
| Entrez ID | 7532 |
| Gene full name | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide |
| Other gene symbols | 14-3-3GAMMA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0005080 | Protein kinase C binding | IPI | molecular_function |
| GO:0005159 | Insulin-like growth factor receptor binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006469 | Negative regulation of protein kinase activity | NAS | biological_process |
| GO:0006605 | Protein targeting | IEA | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0008426 | Protein kinase C inhibitor activity | NAS | molecular_function |
| GO:0009966 | Regulation of signal transduction | NAS | biological_process |
| GO:0019904 | Protein domain specific binding | IEA | molecular_function |
| GO:0030659 | Cytoplasmic vesicle membrane | TAS | cellular_component |
| GO:0030971 | Receptor tyrosine kinase binding | IEA | molecular_function |
| GO:0032869 | Cellular response to insulin stimulus | IEA | biological_process |
| GO:0045664 | Regulation of neuron differentiation | IMP | biological_process |
| GO:0048167 | Regulation of synaptic plasticity | IMP | biological_process |
| GO:0070062 | Extracellular vesicular exosome | IDA | cellular_component |
| GO:0071901 | Negative regulation of protein serine/threonine kinase activity | NAS | biological_process |
| GO:0097193 | Intrinsic apoptotic signaling pathway | TAS | biological_process |
| GO:1900740 | Positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4218717944 | 0.8847272292 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0016059721 |
| GSE13712_SHEAR | Up | 0.0138389154 |
| GSE13712_STATIC | Up | 0.0490764250 |
| GSE19018 | Down | -0.1132245386 |
| GSE19899_A1 | Up | 0.2780817638 |
| GSE19899_A2 | Up | 0.1315523620 |
| PubMed_21979375_A1 | Down | -0.0733579660 |
| PubMed_21979375_A2 | Up | 0.1373739827 |
| GSE35957 | Up | 0.1185373903 |
| GSE36640 | Up | 0.1600172553 |
| GSE54402 | Up | 0.1011207148 |
| GSE9593 | Up | 0.1363951783 |
| GSE43922 | Up | 0.1136940392 |
| GSE24585 | Up | 0.0223234501 |
| GSE37065 | Down | -0.1788622324 |
| GSE28863_A1 | Down | -0.1196981292 |
| GSE28863_A2 | Up | 0.4097875589 |
| GSE28863_A3 | Up | 0.1331195705 |
| GSE28863_A4 | Down | -0.1402862012 |
| GSE48662 | Down | -0.0221901041 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-141-3p | MIMAT0000432 | MIRT006730 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 22537031 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT027922 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-132-5p | MIMAT0004594 | MIRT038650 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046644 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051462 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
