HCSGD entry for YWHAB

1. General information

Official gene symbolYWHAB
Entrez ID7529
Gene full nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
Other gene symbolsGW128 HS1 KCIP-1 YWHAA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000165MAPK cascadeTASbiological_process
GO:0000186Activation of MAPKK activityTASbiological_process
GO:0003714Transcription corepressor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDA IEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006605Protein targetingIEAbiological_process
GO:0006915Apoptotic processTASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0007265Ras protein signal transductionTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008022Protein C-terminus bindingIEAmolecular_function
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0017053Transcriptional repressor complexIEAcellular_component
GO:0019899Enzyme bindingIPImolecular_function
GO:0019904Protein domain specific bindingIEA IPImolecular_function
GO:0030659Cytoplasmic vesicle membraneTAScellular_component
GO:0032403Protein complex bindingIEAmolecular_function
GO:0035308Negative regulation of protein dephosphorylationIDAbiological_process
GO:0035329Hippo signalingTASbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0042470MelanosomeIEAcellular_component
GO:0042826Histone deacetylase bindingIPImolecular_function
GO:0043085Positive regulation of catalytic activityIDAbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIEAbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0050815Phosphoserine bindingIPImolecular_function
GO:0051219Phosphoprotein bindingIPImolecular_function
GO:0051220Cytoplasmic sequestering of proteinIDAbiological_process
GO:0051291Protein heterooligomerizationIEAbiological_process
GO:0070062Extracellular vesicular exosomeIDAcellular_component
GO:0097193Intrinsic apoptotic signaling pathwayTASbiological_process
GO:1900740Positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.30925389230.91520631060.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2193123050
GSE13712_SHEARUp0.2485609601
GSE13712_STATICUp0.0881742610
GSE19018Down-0.1141531691
GSE19899_A1Up0.0803149478
GSE19899_A2Up0.1126861327
PubMed_21979375_A1Up0.1556167700
PubMed_21979375_A2Up0.1877887038
GSE35957Down-0.0668953602
GSE36640Down-0.0238455302
GSE54402Up0.0821633014
GSE9593Up0.2370797154
GSE43922Up0.1091390878
GSE24585Down-0.2541187979
GSE37065Up0.0732464790
GSE28863_A1Up0.1214573482
GSE28863_A2Down-0.0039323085
GSE28863_A3Down-0.4009235342
GSE28863_A4Up0.1841256371
GSE48662Up0.0646812584

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1301-3pMIMAT0005797MIRT035990CLASHFunctional MTI (Weak)23622248
hsa-miR-877-3pMIMAT0004950MIRT037014CLASHFunctional MTI (Weak)23622248
hsa-miR-378a-5pMIMAT0000731MIRT044012CLASHFunctional MTI (Weak)23622248
hsa-miR-221-3pMIMAT0000278MIRT046917CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.