HCSGD entry for WNT8A
1. General information
| Official gene symbol | WNT8A |
|---|---|
| Entrez ID | 7478 |
| Gene full name | wingless-type MMTV integration site family, member 8A |
| Other gene symbols | WNT8D |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005102 | Receptor binding | IEA | molecular_function |
| GO:0005109 | Frizzled binding | NAS | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005578 | Proteinaceous extracellular matrix | IEA ISS | cellular_component |
| GO:0005615 | Extracellular space | IBA ISS | cellular_component |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0007492 | Endoderm development | IEA | biological_process |
| GO:0009949 | Polarity specification of anterior/posterior axis | IEA | biological_process |
| GO:0010085 | Polarity specification of proximal/distal axis | IEA | biological_process |
| GO:0010469 | Regulation of receptor activity | NAS | biological_process |
| GO:0014034 | Neural crest cell fate commitment | ISS | biological_process |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0030182 | Neuron differentiation | IBA | biological_process |
| GO:0032526 | Response to retinoic acid | NAS | biological_process |
| GO:0032880 | Regulation of protein localization | IEA | biological_process |
| GO:0044324 | Regulation of transcription involved in anterior/posterior axis specification | ISS | biological_process |
| GO:0044335 | Canonical Wnt signaling pathway involved in neural crest cell differentiation | ISS | biological_process |
| GO:0048018 | Receptor agonist activity | NAS | molecular_function |
| GO:0048561 | Establishment of organ orientation | IEA | biological_process |
| GO:0060021 | Palate development | IMP | biological_process |
| GO:0060070 | Canonical Wnt signaling pathway | ISS NAS | biological_process |
| GO:0061317 | Canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment | IEP | biological_process |
| GO:2000273 | Positive regulation of receptor activity | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5105427795 | 0.9093766802 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0171788519 |
| GSE13712_SHEAR | Down | -0.0251031804 |
| GSE13712_STATIC | Down | -0.0532868902 |
| GSE19018 | Down | -0.0401564918 |
| GSE19899_A1 | Down | -0.0026775609 |
| GSE19899_A2 | Up | 0.1700028369 |
| PubMed_21979375_A1 | Down | -0.0009548841 |
| PubMed_21979375_A2 | Up | 0.0146768195 |
| GSE35957 | Up | 0.6436245339 |
| GSE36640 | Up | 0.1308201512 |
| GSE54402 | Down | -0.0330609026 |
| GSE9593 | Down | -0.0242987142 |
| GSE43922 | Up | 0.2591834217 |
| GSE24585 | Up | 0.1118792700 |
| GSE37065 | Down | -0.0024612172 |
| GSE28863_A1 | Down | -0.0945403447 |
| GSE28863_A2 | Down | -0.0460815263 |
| GSE28863_A3 | Up | 0.1388472428 |
| GSE28863_A4 | Up | 0.0746268476 |
| GSE48662 | Up | 0.0060105912 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-9-5p | MIMAT0000441 | MIRT021425 | Microarray | Functional MTI (Weak) | 17612493 |
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