HCSGD entry for LAT2
1. General information
| Official gene symbol | LAT2 |
|---|---|
| Entrez ID | 7462 |
| Gene full name | linker for activation of T cells family, member 2 |
| Other gene symbols | LAB NTAL WBSCR15 WBSCR5 WSCR5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019722 | Calcium-mediated signaling | IGI | biological_process |
| GO:0035556 | Intracellular signal transduction | IGI | biological_process |
| GO:0038095 | Fc-epsilon receptor signaling pathway | TAS | biological_process |
| GO:0042113 | B cell activation | IDA TAS | biological_process |
| GO:0042169 | SH2 domain binding | IMP | molecular_function |
| GO:0042629 | Mast cell granule | IEA | cellular_component |
| GO:0043303 | Mast cell degranulation | IEA | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0045121 | Membrane raft | IDA | cellular_component |
| GO:0050853 | B cell receptor signaling pathway | IDA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8861778694 | 0.6536254056 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0620425258 |
| GSE13712_SHEAR | Up | 0.0728777903 |
| GSE13712_STATIC | Up | 0.0114250008 |
| GSE19018 | Up | 0.0098250707 |
| GSE19899_A1 | Down | -0.0220010919 |
| GSE19899_A2 | Up | 0.1666303664 |
| PubMed_21979375_A1 | Down | -0.0362690067 |
| PubMed_21979375_A2 | Up | 0.0238062792 |
| GSE35957 | Up | 0.1131924292 |
| GSE36640 | Down | -0.2501828225 |
| GSE54402 | Up | 0.0527216794 |
| GSE9593 | Down | -0.0240629938 |
| GSE43922 | Up | 0.0389943773 |
| GSE24585 | Down | -0.0204882334 |
| GSE37065 | Up | 0.0005654079 |
| GSE28863_A1 | Down | -0.2073789698 |
| GSE28863_A2 | Down | -0.0387096211 |
| GSE28863_A3 | Up | 0.1103898137 |
| GSE28863_A4 | Up | 0.0127865981 |
| GSE48662 | Down | -0.1960951536 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT005092 | Microarray | Functional MTI (Weak) | 19193853 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25412306 | We identified 107 proteins that could be potential markers of senescence and validated 10 of them (DEP1, NTAL, EBP50, STX4, VAMP3, ARMX3, B2MG, LANCL1, VPS26A and PLD3) |
Entries Per Page
Displaying Page of
