HCSGD entry for EIF4H
1. General information
| Official gene symbol | EIF4H |
|---|---|
| Entrez ID | 7458 |
| Gene full name | eukaryotic translation initiation factor 4H |
| Other gene symbols | WBSCR1 WSCR1 eIF-4H |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003723 | RNA binding | TAS | molecular_function |
| GO:0003743 | Translation initiation factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006413 | Translational initiation | TAS | biological_process |
| GO:0006446 | Regulation of translational initiation | TAS | biological_process |
| GO:0008135 | Translation factor activity, nucleic acid binding | TAS | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016281 | Eukaryotic translation initiation factor 4F complex | TAS | cellular_component |
| GO:0019953 | Sexual reproduction | IEA | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0048589 | Developmental growth | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8213601915 | 0.2199934539 | 0.9999902473 | 0.9030642077 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2586470180 |
| GSE13712_SHEAR | Down | -0.2741595376 |
| GSE13712_STATIC | Down | -0.0366852076 |
| GSE19018 | Down | -0.0594758193 |
| GSE19899_A1 | Up | 0.1650618978 |
| GSE19899_A2 | Up | 0.1383313454 |
| PubMed_21979375_A1 | Up | 0.4745216170 |
| PubMed_21979375_A2 | Up | 0.2041242829 |
| GSE35957 | Down | -0.1676341930 |
| GSE36640 | Down | -0.3739027122 |
| GSE54402 | Up | 0.1182454222 |
| GSE9593 | Down | -0.2229631344 |
| GSE43922 | Up | 0.0777511363 |
| GSE24585 | Down | -0.0683703704 |
| GSE37065 | Down | -0.3091064699 |
| GSE28863_A1 | Up | 0.1191838435 |
| GSE28863_A2 | Up | 0.3687203814 |
| GSE28863_A3 | Down | -0.3022759928 |
| GSE28863_A4 | Down | -0.2247860141 |
| GSE48662 | Down | -0.3917867126 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-24-3p | MIMAT0000080 | MIRT030493 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-941 | MIMAT0004984 | MIRT036572 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038863 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043929 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-185-5p | MIMAT0000455 | MIRT045348 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045559 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047639 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-197-3p | MIMAT0000227 | MIRT048050 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
