HCSGD entry for VIL1

1. General information

Official gene symbolVIL1
Entrez ID7429
Gene full namevillin 1
Other gene symbolsD2S1471 VIL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001726RuffleIDAcellular_component
GO:0003779Actin bindingIEAmolecular_function
GO:0005509Calcium ion bindingIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005546Phosphatidylinositol-4,5-bisphosphate bindingIDAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005902MicrovillusIDAcellular_component
GO:0006461Protein complex assemblyTASbiological_process
GO:0007010Cytoskeleton organizationIEAbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayIDAbiological_process
GO:0008360Regulation of cell shapeIDAbiological_process
GO:0009617Response to bacteriumIDAbiological_process
GO:0010634Positive regulation of epithelial cell migrationIDAbiological_process
GO:0030027LamellipodiumIDA IEAcellular_component
GO:0030041Actin filament polymerizationIDAbiological_process
GO:0030042Actin filament depolymerizationIDAbiological_process
GO:0030175FilopodiumIDAcellular_component
GO:0030335Positive regulation of cell migrationIDAbiological_process
GO:0032233Positive regulation of actin filament bundle assemblyIDAbiological_process
GO:0032432Actin filament bundleIDAcellular_component
GO:0032433Filopodium tipIEA ISScellular_component
GO:0035727Lysophosphatidic acid bindingIDAmolecular_function
GO:0035729Cellular response to hepatocyte growth factor stimulusIEAbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043027Cysteine-type endopeptidase inhibitor activity involved in apoptotic processIEA ISSmolecular_function
GO:0051014Actin filament severingIDAbiological_process
GO:0051015Actin filament bindingIDAmolecular_function
GO:0051125Regulation of actin nucleationIDAbiological_process
GO:0051693Actin filament cappingIDAbiological_process
GO:0060327Cytoplasmic actin-based contraction involved in cell motilityIDAbiological_process
GO:0061041Regulation of wound healingIEA ISSbiological_process
GO:0071364Cellular response to epidermal growth factor stimulusIDAbiological_process
GO:2000392Regulation of lamellipodium morphogenesisIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.88694182970.83351961550.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0541554872
GSE13712_SHEARDown-0.0175969283
GSE13712_STATICDown-0.0567758596
GSE19018Up0.0871241736
GSE19899_A1Down-0.0009535042
GSE19899_A2Up0.0342090672
PubMed_21979375_A1Down-0.1429363261
PubMed_21979375_A2Down-0.0662815384
GSE35957Down-0.0668090663
GSE36640Up0.0487910279
GSE54402Down-0.0577030397
GSE9593Up0.0892523674
GSE43922Up0.0466335741
GSE24585Up0.0984772940
GSE37065Down-0.0008830785
GSE28863_A1Down-0.0552938684
GSE28863_A2Up0.0093244533
GSE28863_A3Up0.0873594612
GSE28863_A4Up0.1100666925
GSE48662Down-0.0214387344

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.