HCSGD entry for VEGFC

1. General information

Official gene symbolVEGFC
Entrez ID7424
Gene full namevascular endothelial growth factor C
Other gene symbolsFlt4-L VRP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIEAbiological_process
GO:0002052Positive regulation of neuroblast proliferationIEAbiological_process
GO:0002576Platelet degranulationTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0006929Substrate-dependent cell migrationTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0008284Positive regulation of cell proliferationTASbiological_process
GO:0009887Organ morphogenesisIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016331Morphogenesis of embryonic epitheliumIEAbiological_process
GO:0030168Platelet activationTASbiological_process
GO:0030947Regulation of vascular endothelial growth factor receptor signaling pathwayIEAbiological_process
GO:0031093Platelet alpha granule lumenTAScellular_component
GO:0031954Positive regulation of protein autophosphorylationIEAbiological_process
GO:0042056Chemoattractant activityIDAmolecular_function
GO:0042493Response to drugIEAbiological_process
GO:0043185Vascular endothelial growth factor receptor 3 bindingIEAmolecular_function
GO:0043536Positive regulation of blood vessel endothelial cell migrationIEAbiological_process
GO:0045776Negative regulation of blood pressureIEAbiological_process
GO:0048010Vascular endothelial growth factor receptor signaling pathwayTASbiological_process
GO:0050679Positive regulation of epithelial cell proliferationIEAbiological_process
GO:0050714Positive regulation of protein secretionIEAbiological_process
GO:0050918Positive chemotaxisIDAbiological_process
GO:0050930Induction of positive chemotaxisIDAbiological_process
GO:0051781Positive regulation of cell divisionIEAbiological_process
GO:0060754Positive regulation of mast cell chemotaxisIDAbiological_process
GO:1901492Positive regulation of lymphangiogenesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02629525850.36737721970.37852478171.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5011460957
GSE13712_SHEARUp0.3137401945
GSE13712_STATICUp0.4216292503
GSE19018Down-0.4565820444
GSE19899_A1Up0.1901515141
GSE19899_A2Up1.6013127023
PubMed_21979375_A1Up0.0994828038
PubMed_21979375_A2Up0.6941637760
GSE35957Down-0.0293189380
GSE36640Up1.0151120433
GSE54402Up0.7259188833
GSE9593Down-0.1502077525
GSE43922Up0.5288795334
GSE24585Down-0.2722723940
GSE37065Up0.4086900611
GSE28863_A1Up0.0483055920
GSE28863_A2Up0.5130187525
GSE28863_A3Down-0.4567547907
GSE28863_A4Down-0.1977121437
GSE48662Down-0.7515750459

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-128-3pMIMAT0000424MIRT021989MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.