HCSGD entry for VEGFB

1. General information

Official gene symbolVEGFB
Entrez ID7423
Gene full namevascular endothelial growth factor B
Other gene symbolsVEGFL VRF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIEAbiological_process
GO:0001938Positive regulation of endothelial cell proliferationIDAbiological_process
GO:0002576Platelet degranulationTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0006493Protein O-linked glycosylationIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0008201Heparin bindingIEAmolecular_function
GO:0010629Negative regulation of gene expressionIDAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0030168Platelet activationTASbiological_process
GO:0030949Positive regulation of vascular endothelial growth factor receptor signaling pathwayIDAbiological_process
GO:0031093Platelet alpha granule lumenTAScellular_component
GO:0035470Positive regulation of vascular wound healingIDAbiological_process
GO:0042056Chemoattractant activityIDAmolecular_function
GO:0042493Response to drugIEAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0043066Negative regulation of apoptotic processIDAbiological_process
GO:0043117Positive regulation of vascular permeabilityIDAbiological_process
GO:0043183Vascular endothelial growth factor receptor 1 bindingIPImolecular_function
GO:0043524Negative regulation of neuron apoptotic processIDAbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0048010Vascular endothelial growth factor receptor signaling pathwayTASbiological_process
GO:0050731Positive regulation of peptidyl-tyrosine phosphorylationIDAbiological_process
GO:0050918Positive chemotaxisIDAbiological_process
GO:0050930Induction of positive chemotaxisIDAbiological_process
GO:0051781Positive regulation of cell divisionIEAbiological_process
GO:0051897Positive regulation of protein kinase B signalingIDAbiological_process
GO:0060048Cardiac muscle contractionIEAbiological_process
GO:0060754Positive regulation of mast cell chemotaxisIDAbiological_process
GO:0060976Coronary vasculature developmentIEAbiological_process
GO:0070374Positive regulation of ERK1 and ERK2 cascadeIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.36814733480.06206333350.99999024730.4696863140

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1827438804
GSE13712_SHEARDown-0.7239502295
GSE13712_STATICDown-0.5070176324
GSE19018Up0.3475380897
GSE19899_A1Down-0.4738716145
GSE19899_A2Up0.0587662350
PubMed_21979375_A1Down0.0000000000
PubMed_21979375_A2Down-0.2044597402
GSE35957Down-0.4668479342
GSE36640Down-0.1371330993
GSE54402Down-0.0628701151
GSE9593Up0.6717446657
GSE43922Down-0.3305847599
GSE24585Down-0.1033640377
GSE37065Up0.1975527336
GSE28863_A1Down-0.2608773023
GSE28863_A2Up0.7134511921
GSE28863_A3Up0.0960647985
GSE28863_A4Down-0.1788304149
GSE48662Up0.2818180257

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AfliberceptDB08885 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.