HCSGD entry for VDAC2
1. General information
| Official gene symbol | VDAC2 |
|---|---|
| Entrez ID | 7417 |
| Gene full name | voltage-dependent anion channel 2 |
| Other gene symbols | POR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | IEA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0006820 | Anion transport | TAS | biological_process |
| GO:0008308 | Voltage-gated anion channel activity | IEA TAS | molecular_function |
| GO:0015288 | Porin activity | IEA | molecular_function |
| GO:0032272 | Negative regulation of protein polymerization | IEA | biological_process |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0034765 | Regulation of ion transmembrane transport | TAS | biological_process |
| GO:0042645 | Mitochondrial nucleoid | IDA | cellular_component |
| GO:0046930 | Pore complex | IEA | cellular_component |
| GO:2001243 | Negative regulation of intrinsic apoptotic signaling pathway | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2490937730 | 0.9393568557 | 0.9375657372 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3495459645 |
| GSE13712_SHEAR | Down | -0.0430610360 |
| GSE13712_STATIC | Up | 0.0849311276 |
| GSE19018 | Up | 0.3973856858 |
| GSE19899_A1 | Up | 0.2336926683 |
| GSE19899_A2 | Up | 0.2213231260 |
| PubMed_21979375_A1 | Up | 0.1934035010 |
| PubMed_21979375_A2 | Up | 0.0528085267 |
| GSE35957 | Down | -0.3070329851 |
| GSE36640 | Up | 0.2874994755 |
| GSE54402 | Up | 0.1878024515 |
| GSE9593 | Up | 0.0461587880 |
| GSE43922 | Up | 0.0653410182 |
| GSE24585 | Down | -0.2254507702 |
| GSE37065 | Down | -0.0603070454 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.2877173197 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-132-3p | MIMAT0000426 | MIRT021858 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-320a | MIMAT0000510 | MIRT044736 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046413 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048258 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
