HCSGD entry for UROD

1. General information

Official gene symbolUROD
Entrez ID7389
Gene full nameuroporphyrinogen decarboxylase
Other gene symbolsPCT UPD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004853Uroporphyrinogen decarboxylase activityIDA IEA TASmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006778Porphyrin-containing compound metabolic processTASbiological_process
GO:0006779Porphyrin-containing compound biosynthetic processIEAbiological_process
GO:0006782Protoporphyrinogen IX biosynthetic processIEAbiological_process
GO:0006783Heme biosynthetic processIC TASbiological_process
GO:0015630Microtubule cytoskeletonIDAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.12539824850.91458003880.72254975921.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5942411929
GSE13712_SHEARUp0.0538184350
GSE13712_STATICUp0.1765021694
GSE19018Up0.1075703539
GSE19899_A1Up0.0694152586
GSE19899_A2Up0.3022695712
PubMed_21979375_A1Up0.2103334899
PubMed_21979375_A2Up0.2579982920
GSE35957Down-0.1052862991
GSE36640Up0.0530036060
GSE54402Up0.0257964409
GSE9593Down-0.0395859240
GSE43922Down-0.1258924104
GSE24585Up0.2800310881
GSE37065Down-0.2530453377
GSE28863_A1Up0.2235014609
GSE28863_A2Up0.2399931919
GSE28863_A3Up0.4363729259
GSE28863_A4Down-0.1049635021
GSE48662Down-0.1213242652

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Coproporphyrin IDB03727 EXPT00070
Coproporphyrin IiiDB04461 EXPT00993

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-92b-3pMIMAT0003218MIRT040550CLASHFunctional MTI (Weak)23622248
hsa-miR-222-3pMIMAT0000279MIRT046708CLASHFunctional MTI (Weak)23622248
hsa-miR-10b-5pMIMAT0000254MIRT047424CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.