HCSGD entry for UCK2

1. General information

Official gene symbolUCK2
Entrez ID7371
Gene full nameuridine-cytidine kinase 2
Other gene symbolsTSA903 UK UMPK
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004849Uridine kinase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005575Cellular_componentNDcellular_component
GO:0005829CytosolTAScellular_component
GO:0006206Pyrimidine nucleobase metabolic processTASbiological_process
GO:0007631Feeding behaviorIEAbiological_process
GO:0016773Phosphotransferase activity, alcohol group as acceptorIEAmolecular_function
GO:0019206Nucleoside kinase activityEXPmolecular_function
GO:0043097Pyrimidine nucleoside salvageTASbiological_process
GO:0043231Intracellular membrane-bounded organelleIEAcellular_component
GO:0044206UMP salvageIEAbiological_process
GO:0044211CTP salvageIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0048678Response to axon injuryIEAbiological_process
GO:0055086Nucleobase-containing small molecule metabolic processTASbiological_process
GO:0071453Cellular response to oxygen levelsIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.58231998020.92921829340.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.1481608531
GSE28863_A2Up0.7970800736
GSE28863_A3Up0.0356853036
GSE28863_A4Down-0.0593489736
GSE48662Down-0.3313345609

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

CytidineDB02097 EXPT01051
Cytidine-5'-TriphosphateDB02431 EXPT01053
Cytidine-5'-MonophosphateDB03403 EXPT00796
Uridine 5'-TriphosphateDB04005 EXPT03210
Citric AcidDB04272 EXPT00922

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-34a-5pMIMAT0000255MIRT025567ProteomicsFunctional MTI (Weak)21566225
hsa-let-7b-5pMIMAT0000063MIRT032462ProteomicsFunctional MTI (Weak)18668040
hsa-miR-361-5pMIMAT0000703MIRT044088CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.