HCSGD entry for UCP1
1. General information
| Official gene symbol | UCP1 |
|---|---|
| Entrez ID | 7350 |
| Gene full name | uncoupling protein 1 (mitochondrial, proton carrier) |
| Other gene symbols | SLC25A7 UCP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0006839 | Mitochondrial transport | IEA | biological_process |
| GO:0015992 | Proton transport | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0017077 | Oxidative phosphorylation uncoupler activity | IEA | molecular_function |
| GO:0022904 | Respiratory electron transport chain | TAS | biological_process |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050873 | Brown fat cell differentiation | ISS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7021166597 | 0.8110719464 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0541692378 |
| GSE13712_SHEAR | Up | 0.0894860002 |
| GSE13712_STATIC | Up | 0.1314990057 |
| GSE19018 | Up | 0.0381668665 |
| GSE19899_A1 | Down | -0.0212623729 |
| GSE19899_A2 | Up | 0.0484925016 |
| PubMed_21979375_A1 | Up | 0.2219428925 |
| PubMed_21979375_A2 | Down | -0.0884815930 |
| GSE35957 | Up | 0.0674774332 |
| GSE36640 | Up | 0.1298954978 |
| GSE54402 | Down | -0.0452448393 |
| GSE9593 | Up | 0.2175200060 |
| GSE43922 | Up | 0.0118351636 |
| GSE24585 | Down | -0.0222956449 |
| GSE37065 | Down | -0.0453229779 |
| GSE28863_A1 | Up | 0.0218733433 |
| GSE28863_A2 | Down | -0.1278867158 |
| GSE28863_A3 | Up | 0.1487072142 |
| GSE28863_A4 | Up | 0.0065518942 |
| GSE48662 | Up | 0.0486764685 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 22970173 | We hypothesize that nitric oxide may modulate senescence in CD; epithelial cells of CD had higher levels of NOS2 expression than in UC (P = 0 |
| 10603304 | Regulation of energy metabolism in human cells in aging and diabetes: FoF(1), mtDNA, UCP, and ROS |
| 10603304 | Recent advances in bioenergetics consist of discoveries related to rotational coupling in ATP synthase (FoF(1)), uncoupling proteins (UCP), reactive oxygen species (ROS) and mitochondrial DNA (mtDNA) |
| 10603304 | The expression of both mtDNA (by mtTFA) and nDNA for oxphos and UCP (by NRFs, etc |
Entries Per Page
Displaying Page of
