HCSGD entry for UBE2V1

1. General information

Official gene symbolUBE2V1
Entrez ID7335
Gene full nameubiquitin-conjugating enzyme E2 variant 1
Other gene symbolsCIR1 CROC-1 CROC1 UBE2V UEV-1 UEV1 UEV1A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000151Ubiquitin ligase complexIDAcellular_component
GO:0000209Protein polyubiquitinationTASbiological_process
GO:0002224Toll-like receptor signaling pathwayTASbiological_process
GO:0002755MyD88-dependent toll-like receptor signaling pathwayTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusTAScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006282Regulation of DNA repairTASbiological_process
GO:0006355Regulation of transcription, DNA-templatedTASbiological_process
GO:0016881Acid-amino acid ligase activityIEAmolecular_function
GO:0030154Cell differentiationNASbiological_process
GO:0031371Ubiquitin conjugating enzyme complexIDAcellular_component
GO:0034134Toll-like receptor 2 signaling pathwayTASbiological_process
GO:0034142Toll-like receptor 4 signaling pathwayTASbiological_process
GO:0034146Toll-like receptor 5 signaling pathwayTASbiological_process
GO:0034162Toll-like receptor 9 signaling pathwayTASbiological_process
GO:0034166Toll-like receptor 10 signaling pathwayTASbiological_process
GO:0035370UBC13-UEV1A complexIDAcellular_component
GO:0035872Nucleotide-binding domain, leucine rich repeat containing receptor signaling pathwayTASbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0038123Toll-like receptor TLR1:TLR2 signaling pathwayTASbiological_process
GO:0038124Toll-like receptor TLR6:TLR2 signaling pathwayTASbiological_process
GO:0043123Positive regulation of I-kappaB kinase/NF-kappaB signalingIMP TASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedTASbiological_process
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:0051092Positive regulation of NF-kappaB transcription factor activityIMPbiological_process
GO:0070423Nucleotide-binding oligomerization domain containing signaling pathwayTASbiological_process
GO:0070534Protein K63-linked ubiquitinationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.70991657990.83991321000.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Up0.0383900287
GSE24585Up0.0826998292
GSE37065Up0.0542536856
GSE28863_A1Down-0.2853580043
GSE28863_A2Down-0.2242003981
GSE28863_A3Up0.3585583308
GSE28863_A4Down-0.1243646584
GSE48662Up0.1769456513

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT001400pSILACFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.