HCSGD entry for UBE2E1

1. General information

Official gene symbolUBE2E1
Entrez ID7324
Gene full nameubiquitin-conjugating enzyme E2E 1
Other gene symbolsUBCH6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000151Ubiquitin ligase complexIDAcellular_component
GO:0000209Protein polyubiquitinationIDAbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0004842Ubiquitin-protein ligase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006511Ubiquitin-dependent protein catabolic processTASbiological_process
GO:0007094Mitotic spindle assembly checkpointTASbiological_process
GO:0010390Histone monoubiquitinationIDAbiological_process
GO:0016567Protein ubiquitinationIDA IEAbiological_process
GO:0016881Acid-amino acid ligase activityIEAmolecular_function
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0031145Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processTASbiological_process
GO:0032020ISG15-protein conjugationIDAbiological_process
GO:0033523Histone H2B ubiquitinationIDAbiological_process
GO:0042296ISG15 ligase activityIDAmolecular_function
GO:0051436Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051437Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051439Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0070936Protein K48-linked ubiquitinationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.14033002930.86062963790.75272604441.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0754663335
GSE13712_SHEARDown-0.0821000125
GSE13712_STATICUp0.0917039358
GSE19018Up0.2206348577
GSE19899_A1Up0.3071762713
GSE19899_A2Up0.4665235522
PubMed_21979375_A1Up0.4653943266
PubMed_21979375_A2Up0.4035562064
GSE35957Up0.1881352919
GSE36640Down-0.1053773405
GSE54402Up0.5426820361
GSE9593Up0.1578262316
GSE43922Up0.4102851061
GSE24585Down-0.2936744571
GSE37065Up0.1220099350
GSE28863_A1Down-0.1722247874
GSE28863_A2Down-0.2353443087
GSE28863_A3Down-0.2563125212
GSE28863_A4Down-0.0210446460
GSE48662Down-0.2103723322

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029169MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.