HCSGD entry for UBE2D2
1. General information
Official gene symbol | UBE2D2 |
---|---|
Entrez ID | 7322 |
Gene full name | ubiquitin-conjugating enzyme E2D 2 |
Other gene symbols | E2(17)KB2 PUBC1 UBC4 UBC4/5 UBCH5B |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0000151 | Ubiquitin ligase complex | IDA | cellular_component |
GO:0000209 | Protein polyubiquitination | IDA | biological_process |
GO:0002224 | Toll-like receptor signaling pathway | TAS | biological_process |
GO:0002756 | MyD88-independent toll-like receptor signaling pathway | TAS | biological_process |
GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005524 | ATP binding | IEA | molecular_function |
GO:0005654 | Nucleoplasm | TAS | cellular_component |
GO:0005829 | Cytosol | TAS | cellular_component |
GO:0006464 | Cellular protein modification process | TAS | biological_process |
GO:0006511 | Ubiquitin-dependent protein catabolic process | TAS | biological_process |
GO:0016567 | Protein ubiquitination | IDA | biological_process |
GO:0016881 | Acid-amino acid ligase activity | IEA | molecular_function |
GO:0034138 | Toll-like receptor 3 signaling pathway | TAS | biological_process |
GO:0034142 | Toll-like receptor 4 signaling pathway | TAS | biological_process |
GO:0035666 | TRIF-dependent toll-like receptor signaling pathway | TAS | biological_process |
GO:0045087 | Innate immune response | TAS | biological_process |
GO:0061418 | Regulation of transcription from RNA polymerase II promoter in response to hypoxia | TAS | biological_process |
GO:0070936 | Protein K48-linked ubiquitination | IDA | biological_process |
GO:0071456 | Cellular response to hypoxia | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.6225636222 | 0.7009324456 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Up | 0.0997636450 |
GSE13712_SHEAR | Down | -0.2265915813 |
GSE13712_STATIC | Down | -0.1530708268 |
GSE19018 | Up | 0.0078996774 |
GSE19899_A1 | Down | -0.0092181116 |
GSE19899_A2 | Up | 0.1226641838 |
PubMed_21979375_A1 | Down | -0.2778117390 |
PubMed_21979375_A2 | Down | -0.0134456735 |
GSE35957 | Down | -0.1988808440 |
GSE36640 | Down | -0.2371667587 |
GSE54402 | Up | 0.1906983374 |
GSE9593 | Up | 0.1636550291 |
GSE43922 | Up | 0.0859302261 |
GSE24585 | Up | 0.1138315561 |
GSE37065 | Up | 0.0601428068 |
GSE28863_A1 | Up | 0.1610189010 |
GSE28863_A2 | Up | 0.3909086042 |
GSE28863_A3 | Down | -0.2639518487 |
GSE28863_A4 | Down | -0.2453232606 |
GSE48662 | Up | 0.3252594204 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
---|---|---|
(R,R)-2,3-Butanediol | DB02418 | EXPT00773 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-155-5p | MIMAT0000646 | MIRT020586 | Proteomics | Functional MTI (Weak) | 18668040 |
hsa-miR-215-5p | MIMAT0000272 | MIRT024527 | Microarray | Functional MTI (Weak) | 19074876 |
hsa-miR-192-5p | MIMAT0000222 | MIRT026243 | Microarray | Functional MTI (Weak) | 19074876 |
hsa-let-7b-5p | MIMAT0000063 | MIRT032280 | Proteomics | Functional MTI (Weak) | 18668040 |
hsa-miR-10a-5p | MIMAT0000253 | MIRT047680 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-30c-5p | MIMAT0000244 | MIRT047862 | CLASH | Functional MTI (Weak) | 23622248 |
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