HCSGD entry for TNFRSF4

1. General information

Official gene symbolTNFRSF4
Entrez ID7293
Gene full nametumor necrosis factor receptor superfamily, member 4
Other gene symbolsACT35 CD134 OX40 TXGP1L
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005031Tumor necrosis factor-activated receptor activityIEAmolecular_function
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006954Inflammatory responseIEAbiological_process
GO:0006955Immune responseTASbiological_process
GO:0006968Cellular defense responseIEAbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0009986Cell surfaceISScellular_component
GO:0012501Programmed cell deathTASbiological_process
GO:0030890Positive regulation of B cell proliferationISSbiological_process
GO:0042098T cell proliferationISSbiological_process
GO:0042981Regulation of apoptotic processIEAbiological_process
GO:0043433Negative regulation of sequence-specific DNA binding transcription factor activityISSbiological_process
GO:0045859Regulation of protein kinase activityIEAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedISSbiological_process
GO:0050710Negative regulation of cytokine secretionIEAbiological_process
GO:0051024Positive regulation of immunoglobulin secretionISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.26483774550.91949859430.95988981701.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2126738835
GSE13712_SHEARDown-0.0843429459
GSE13712_STATICDown-0.0618735735
GSE19018Up0.1012861497
GSE19899_A1Up0.0202885062
GSE19899_A2Up0.3132841390
PubMed_21979375_A1Up0.3048494800
PubMed_21979375_A2Down-0.0561795218
GSE35957Up0.0541274603
GSE36640Up0.4366859897
GSE54402Up0.2161498382
GSE9593Down-0.0238993684
GSE43922Up0.2177072806
GSE24585Up0.1076893848
GSE37065Down-0.2007779897
GSE28863_A1Down-0.0129892424
GSE28863_A2Up0.1170410368
GSE28863_A3Up0.4272595938
GSE28863_A4Up0.1069958299
GSE48662Up0.0353347959

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.