HCSGD entry for CDK11A

1. General information

Official gene symbolCDK11A
Entrez ID728642
Gene full namecyclin-dependent kinase 11A
Other gene symbolsCDC2L2 CDC2L3 CDK11-p110 CDK11-p46 CDK11-p58 PITSLRE p58GTA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001558Regulation of cell growthIEPbiological_process
GO:0001824Blastocyst developmentIEAbiological_process
GO:0004672Protein kinase activityNASmolecular_function
GO:0004674Protein serine/threonine kinase activityIDA IEAmolecular_function
GO:0004693Cyclin-dependent protein serine/threonine kinase activityIEAmolecular_function
GO:0005524ATP bindingIDA IEAmolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0006468Protein phosphorylationIDAbiological_process
GO:0006915Apoptotic processNASbiological_process
GO:0007067MitosisNASbiological_process
GO:0007088Regulation of mitosisIEAbiological_process
GO:0050684Regulation of mRNA processingIDAbiological_process
GO:2001234Negative regulation of apoptotic signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.61469232550.93717237950.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Down-0.1023923375
GSE24585Up0.2985102793
GSE37065Up0.1249262437
GSE28863_A1Up0.0439542460
GSE28863_A2Up0.1476514116
GSE28863_A3Up0.0124584559
GSE28863_A4Up0.0183168375
GSE48662Down-0.0028470943

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-3pMIMAT0004950MIRT037092CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049054CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.