HCSGD entry for TUBG1
1. General information
| Official gene symbol | TUBG1 |
|---|---|
| Entrez ID | 7283 |
| Gene full name | tubulin, gamma 1 |
| Other gene symbols | GCP-1 TUBG TUBGCP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000212 | Meiotic spindle organization | ISS | biological_process |
| GO:0000226 | Microtubule cytoskeleton organization | TAS | biological_process |
| GO:0000242 | Pericentriolar material | IEA | cellular_component |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000794 | Condensed nuclear chromosome | ISS | cellular_component |
| GO:0000930 | Gamma-tubulin complex | IEA TAS | cellular_component |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005200 | Structural constituent of cytoskeleton | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA ISS | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005814 | Centriole | IEA | cellular_component |
| GO:0005827 | Polar microtubule | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0005881 | Cytoplasmic microtubule | IEA | cellular_component |
| GO:0007020 | Microtubule nucleation | IEA | biological_process |
| GO:0031122 | Cytoplasmic microtubule organization | IEA | biological_process |
| GO:0031252 | Cell leading edge | IEA | cellular_component |
| GO:0031513 | Nonmotile primary cilium | IEA | cellular_component |
| GO:0036064 | Ciliary basal body | IEA | cellular_component |
| GO:0045177 | Apical part of cell | IEA | cellular_component |
| GO:0051258 | Protein polymerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6396794727 | 0.2671554272 | 0.9999902473 | 0.9890025176 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2359735531 |
| GSE13712_SHEAR | Down | -0.0671086414 |
| GSE13712_STATIC | Down | -0.0931818781 |
| GSE19018 | Down | -0.0319759475 |
| GSE19899_A1 | Up | 0.0073931599 |
| GSE19899_A2 | Up | 0.0540158874 |
| PubMed_21979375_A1 | Up | 0.8532590849 |
| PubMed_21979375_A2 | Up | 0.0906670345 |
| GSE35957 | Down | -0.9435510855 |
| GSE36640 | Down | -0.3830378959 |
| GSE54402 | Up | 0.3266563604 |
| GSE9593 | Down | -0.5377136138 |
| GSE43922 | Up | 0.0337780174 |
| GSE24585 | Down | -0.1400524813 |
| GSE37065 | Up | 0.0960239249 |
| GSE28863_A1 | Down | -0.1962839121 |
| GSE28863_A2 | Up | 0.0741390878 |
| GSE28863_A3 | Down | -0.1163572258 |
| GSE28863_A4 | Down | -0.0132542867 |
| GSE48662 | Down | -0.2351500819 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Vinblastine | DB00570 | APRD00708 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036349 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042839 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT043581 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-187-3p | MIMAT0000262 | MIRT047028 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048681 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050164 | CLASH | Functional MTI (Weak) | 23622248 |
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