HCSGD entry for TTF1
1. General information
| Official gene symbol | TTF1 |
|---|---|
| Entrez ID | 7270 |
| Gene full name | transcription termination factor, RNA polymerase I |
| Other gene symbols | TTF-1 TTF-I |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0005634 | Nucleus | NAS | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0006338 | Chromatin remodeling | IEA | biological_process |
| GO:0006353 | DNA-templated transcription, termination | NAS | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006360 | Transcription from RNA polymerase I promoter | TAS | biological_process |
| GO:0006361 | Transcription initiation from RNA polymerase I promoter | IEA | biological_process |
| GO:0006363 | Termination of RNA polymerase I transcription | TAS | biological_process |
| GO:0008156 | Negative regulation of DNA replication | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8666360397 | 0.1049706622 | 0.9999902473 | 0.6211604494 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2857841094 |
| GSE13712_SHEAR | Down | -0.2016628047 |
| GSE13712_STATIC | Down | -0.1615564786 |
| GSE19018 | Down | -0.1581301796 |
| GSE19899_A1 | Down | -0.2528480086 |
| GSE19899_A2 | Down | -0.2584304674 |
| PubMed_21979375_A1 | Up | 0.4385439083 |
| PubMed_21979375_A2 | Down | -0.5182667178 |
| GSE35957 | Down | -0.5750655114 |
| GSE36640 | Down | -0.7552790497 |
| GSE54402 | Up | 0.1503377239 |
| GSE9593 | Down | -0.4075052778 |
| GSE43922 | Up | 0.0506694945 |
| GSE24585 | Down | -0.0286564256 |
| GSE37065 | Up | 0.0642336821 |
| GSE28863_A1 | Up | 0.0716458009 |
| GSE28863_A2 | Up | 0.0418081140 |
| GSE28863_A3 | Down | -0.3675793180 |
| GSE28863_A4 | Up | 0.2104525731 |
| GSE48662 | Down | -0.2601124145 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020919 | Reporter assay;Other | Non-Functional MTI | 20584899 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
