HCSGD entry for TRPM2
1. General information
| Official gene symbol | TRPM2 |
|---|---|
| Entrez ID | 7226 |
| Gene full name | transient receptor potential cation channel, subfamily M, member 2 |
| Other gene symbols | EREG1 KNP3 LTRPC2 NUDT9H NUDT9L1 TRPC7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005216 | Ion channel activity | IEA | molecular_function |
| GO:0005262 | Calcium channel activity | IEA | molecular_function |
| GO:0005272 | Sodium channel activity | IEA | molecular_function |
| GO:0005384 | Manganese ion transmembrane transporter activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006816 | Calcium ion transport | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
| GO:0033194 | Response to hydroperoxide | IEA | biological_process |
| GO:0047631 | ADP-ribose diphosphatase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4041428213 | 0.7944306029 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1549947313 |
| GSE13712_SHEAR | Up | 0.0152950718 |
| GSE13712_STATIC | Up | 0.3409032117 |
| GSE19018 | Up | 0.1781211854 |
| GSE19899_A1 | Down | -0.1564587630 |
| GSE19899_A2 | Up | 0.2719434976 |
| PubMed_21979375_A1 | Down | -0.3031188044 |
| PubMed_21979375_A2 | Up | 0.2604409442 |
| GSE35957 | Up | 0.0015594363 |
| GSE36640 | Down | -0.1267125894 |
| GSE54402 | Down | -0.1271127287 |
| GSE9593 | Up | 0.2202830356 |
| GSE43922 | Up | 0.0384227292 |
| GSE24585 | Up | 0.0387606026 |
| GSE37065 | Up | 0.0958168884 |
| GSE28863_A1 | Down | -0.1493607349 |
| GSE28863_A2 | Down | -0.0925731566 |
| GSE28863_A3 | Up | 0.3359823980 |
| GSE28863_A4 | Up | 0.1928408889 |
| GSE48662 | Up | 0.0305856145 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-423-3p | MIMAT0001340 | MIRT042627 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
