HCSGD entry for TRPC6

1. General information

Official gene symbolTRPC6
Entrez ID7225
Gene full nametransient receptor potential cation channel, subfamily C, member 6
Other gene symbolsFSGS2 TRP6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005262Calcium channel activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIDA TAScellular_component
GO:0006812Cation transportTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIEAbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0007568AgingIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0015279Store-operated calcium channel activityIEAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0030168Platelet activationTASbiological_process
GO:0032414Positive regulation of ion transmembrane transporter activityIDAbiological_process
GO:0036057Slit diaphragmIEAcellular_component
GO:0051928Positive regulation of calcium ion transportIDAbiological_process
GO:0070301Cellular response to hydrogen peroxideIEAbiological_process
GO:0070679Inositol 1,4,5 trisphosphate bindingIDAmolecular_function
GO:0071456Cellular response to hypoxiaIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10321319480.04560172490.66842012300.4005978993

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0065529267
GSE13712_SHEARUp0.0181485064
GSE13712_STATICUp0.0268880105
GSE19018Up0.2366405928
GSE19899_A1Down-0.2746941973
GSE19899_A2Down-0.7111322405
PubMed_21979375_A1Down-0.2414695704
PubMed_21979375_A2Down-0.3015240261
GSE35957Up0.0400252865
GSE36640Up0.8895426957
GSE54402Down-2.4166919431
GSE9593Down-0.0737977153
GSE43922Up0.0137500677
GSE24585Up0.5800109414
GSE37065Down-0.0481238924
GSE28863_A1Down-1.6667441764
GSE28863_A2Up2.5074945481
GSE28863_A3Up0.3056189381
GSE28863_A4Down-0.0146908694
GSE48662Up0.3634137938

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022827MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.