HCSGD entry for TRIP6
1. General information
| Official gene symbol | TRIP6 |
|---|---|
| Entrez ID | 7205 |
| Gene full name | thyroid hormone receptor interactor 6 |
| Other gene symbols | OIP-1 OIP1 TRIP-6 TRIP6i2 ZRP-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005149 | Interleukin-1 receptor binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005925 | Focal adhesion | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008588 | Release of cytoplasmic sequestered NF-kappaB | IDA | biological_process |
| GO:0019900 | Kinase binding | IPI | molecular_function |
| GO:0030335 | Positive regulation of cell migration | IMP | biological_process |
| GO:0045323 | Interleukin-1 receptor complex | IDA | cellular_component |
| GO:0046966 | Thyroid hormone receptor binding | NAS | molecular_function |
| GO:0048041 | Focal adhesion assembly | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9311057939 | 0.0415317275 | 0.9999902473 | 0.3836592567 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4221870784 |
| GSE13712_SHEAR | Up | 0.2928610646 |
| GSE13712_STATIC | Up | 0.4240317949 |
| GSE19018 | Down | -0.0461137259 |
| GSE19899_A1 | Down | -1.3638287471 |
| GSE19899_A2 | Down | -0.3673231491 |
| PubMed_21979375_A1 | Down | -0.8895890347 |
| PubMed_21979375_A2 | Down | -0.3535077657 |
| GSE35957 | Down | -0.3976141047 |
| GSE36640 | Down | -0.6058137664 |
| GSE54402 | Down | -0.7053991938 |
| GSE9593 | Up | 0.2474023772 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0045626597 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030281 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-484 | MIMAT0002174 | MIRT042285 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045504 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
