HCSGD entry for C3AR1


1. General information

Official gene symbolC3AR1
Entrez ID719
Gene full namecomplement component 3a receptor 1
Other gene symbolsAZ3B C3AR HNFAG09
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002430Complement receptor mediated signaling pathwayTASbiological_process
GO:0004435Phosphatidylinositol phospholipase C activityTASmolecular_function
GO:0004876Complement component C3a receptor activityTASmolecular_function
GO:0004930G-protein coupled receptor activityIGImolecular_function
GO:0004943C3a anaphylatoxin receptor activityIEAmolecular_function
GO:0004982N-formyl peptide receptor activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006935ChemotaxisIEAbiological_process
GO:0006954Inflammatory responseTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIGIbiological_process
GO:0008015Blood circulationTASbiological_process
GO:0008152Metabolic processTASbiological_process
GO:0010575Positive regulation vascular endothelial growth factor productionIEAbiological_process
GO:0010759Positive regulation of macrophage chemotaxisIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0045766Positive regulation of angiogenesisIEAbiological_process
GO:0090023Positive regulation of neutrophil chemotaxisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04045958740.92419091220.45095014811.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1349341396
GSE13712_SHEARUp0.0886583175
GSE13712_STATICUp0.3326124105
GSE19018Up0.1608295255
GSE19899_A1Up0.1118844757
GSE19899_A2Up0.4281197485
PubMed_21979375_A1Down-0.4264679138
PubMed_21979375_A2Up0.1094616871
GSE35957Up0.0140101703
GSE36640Up0.2926197307
GSE54402Up0.1951836792
GSE9593Down-0.3083646149
GSE43922Up0.0705717219
GSE24585Up0.0815777567
GSE37065Up0.7500337064
GSE28863_A1Down-0.0188182270
GSE28863_A2Up0.0767530082
GSE28863_A3Up0.1246829425
GSE28863_A4Down-0.0629983398
GSE48662Up2.1211595377

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.