HCSGD entry for TRAF5
1. General information
| Official gene symbol | TRAF5 |
|---|---|
| Entrez ID | 7188 |
| Gene full name | TNF receptor-associated factor 5 |
| Other gene symbols | MGC:39780 RNF84 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IEA | molecular_function |
| GO:0004871 | Signal transducer activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007165 | Signal transduction | IEA TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008284 | Positive regulation of cell proliferation | IEA | biological_process |
| GO:0009898 | Cytoplasmic side of plasma membrane | ISS | cellular_component |
| GO:0031625 | Ubiquitin protein ligase binding | IPI | molecular_function |
| GO:0031996 | Thioesterase binding | IPI | molecular_function |
| GO:0035631 | CD40 receptor complex | ISS | cellular_component |
| GO:0042981 | Regulation of apoptotic process | IEA | biological_process |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IEA IEP | biological_process |
| GO:0051091 | Positive regulation of sequence-specific DNA binding transcription factor activity | IMP | biological_process |
| GO:0051092 | Positive regulation of NF-kappaB transcription factor activity | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9987291630 | 0.0004257057 | 0.9999902473 | 0.0383732877 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.4407145135 |
| GSE13712_SHEAR | Down | -0.0496685655 |
| GSE13712_STATIC | Down | -0.0926936760 |
| GSE19018 | Down | -0.6560469551 |
| GSE19899_A1 | Down | -0.7963660685 |
| GSE19899_A2 | Down | -1.8172319462 |
| PubMed_21979375_A1 | Down | -1.5010430090 |
| PubMed_21979375_A2 | Down | -1.9007006784 |
| GSE35957 | Down | -0.1717237679 |
| GSE36640 | Down | -1.0172917750 |
| GSE54402 | Down | -0.6586645263 |
| GSE9593 | Down | -0.0618150649 |
| GSE43922 | Down | -1.2091211785 |
| GSE24585 | Down | -0.5035717795 |
| GSE37065 | Down | -0.3949598451 |
| GSE28863_A1 | Down | -0.2102603448 |
| GSE28863_A2 | Down | -0.0234670403 |
| GSE28863_A3 | Down | -0.2056961666 |
| GSE28863_A4 | Down | -0.1434855108 |
| GSE48662 | Down | -0.3132716035 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
