HCSGD entry for NR2C1

1. General information

Official gene symbolNR2C1
Entrez ID7181
Gene full namenuclear receptor subfamily 2, group C, member 1
Other gene symbolsTR2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0003677DNA bindingTASmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0003707Steroid hormone receptor activityIEAmolecular_function
GO:0004872Receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0010467Gene expressionTASbiological_process
GO:0016605PML bodyIEAcellular_component
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0042826Histone deacetylase bindingIEAmolecular_function
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0048386Positive regulation of retinoic acid receptor signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.37519067280.34432423540.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0068431334
GSE13712_SHEARDown-0.0249766887
GSE13712_STATICUp0.1432103872
GSE19018Down-0.0081971776
GSE19899_A1Down-0.0733729657
GSE19899_A2Up0.1227222296
PubMed_21979375_A1Up0.0932950016
PubMed_21979375_A2Up0.2443243317
GSE35957Up0.0209285606
GSE36640Up0.0073826207
GSE54402Down-0.3862128080
GSE9593Down-0.2392356167
GSE43922Up0.0274342810
GSE24585Up0.1155521684
GSE37065Down-0.0056876946
GSE28863_A1Up0.8183770110
GSE28863_A2Up0.2945458247
GSE28863_A3Up0.0161743196
GSE28863_A4Down-0.0696853869
GSE48662Down-0.6913816471

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.