HCSGD entry for TPSAB1
1. General information
| Official gene symbol | TPSAB1 |
|---|---|
| Entrez ID | 7177 |
| Gene full name | tryptase alpha/beta 1 |
| Other gene symbols | TPS1 TPS2 TPSB1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | IEA NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006952 | Defense response | TAS | biological_process |
| GO:0008236 | Serine-type peptidase activity | TAS | molecular_function |
| GO:0022617 | Extracellular matrix disassembly | TAS | biological_process |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0031012 | Extracellular matrix | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9213363512 | 0.8167056951 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0172813326 |
| GSE13712_SHEAR | Up | 0.0436408363 |
| GSE13712_STATIC | Down | -0.0779010224 |
| GSE19018 | Up | 0.1255397984 |
| GSE19899_A1 | Down | -0.0292007112 |
| GSE19899_A2 | Up | 0.0254149833 |
| PubMed_21979375_A1 | Down | -0.1643441335 |
| PubMed_21979375_A2 | Down | -0.1388651688 |
| GSE35957 | Up | 0.0491612947 |
| GSE36640 | Down | -0.0614946398 |
| GSE54402 | Up | 0.0068095441 |
| GSE9593 | Up | 0.0251085668 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0275350632 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Amido Phenyl Pyruvic Acid | DB02018 | EXPT00537 |
| 4-PIPERIDIN-4-YLBUTANAL | DB04654 | - |
| [4-(3-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]-(5-PHENETHYL- PYRIDIN-3-YL)-METHANONE | DB04764 | - |
| (5-(aminomethyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)(5-(phenylethynyl)furan-2-yl)methanone | DB06962 | - |
| 1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanamine | DB06848 | - |
| 1-[1'-(3-phenylacryloyl)spiro[1-benzofuran-3,4'-piperidin]-5-yl]methanamine | DB06849 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
