HCSGD entry for TPM3
1. General information
| Official gene symbol | TPM3 |
|---|---|
| Entrez ID | 7170 |
| Gene full name | tropomyosin 3 |
| Other gene symbols | CFTD NEM1 OK/SW-cl.5 TM-5 TM3 TM30 TM30nm TM5 TPMsk3 TRK hscp30 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001725 | Stress fiber | IDA | cellular_component |
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005604 | Basement membrane | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005856 | Cytoskeleton | NAS TAS | cellular_component |
| GO:0005862 | Muscle thin filament tropomyosin | TAS | cellular_component |
| GO:0006928 | Cellular component movement | TAS | biological_process |
| GO:0006936 | Muscle contraction | TAS | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0030049 | Muscle filament sliding | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8303626610 | 0.3709950306 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0173187166 |
| GSE13712_SHEAR | Up | 0.0218299887 |
| GSE13712_STATIC | Up | 0.0855854477 |
| GSE19018 | Down | -0.1104106828 |
| GSE19899_A1 | Down | -0.0332621565 |
| GSE19899_A2 | Down | -0.0276340193 |
| PubMed_21979375_A1 | Down | -0.3746802195 |
| PubMed_21979375_A2 | Down | -0.3748312643 |
| GSE35957 | Up | 0.0201648855 |
| GSE36640 | Up | 0.0448038127 |
| GSE54402 | Up | 0.0615746431 |
| GSE9593 | Up | 0.0947214858 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.1304495484 |
| GSE28863_A2 | Up | 0.0543473787 |
| GSE28863_A3 | Down | -0.2911666517 |
| GSE28863_A4 | Up | 0.1867399928 |
| GSE48662 | Down | -0.4308944280 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT001325 | pSILAC//Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT001325 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT001403 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-145-5p | MIMAT0000437 | MIRT021512 | Reporter assay;Microarray | Functional MTI | 21351259 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029782 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040208 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049433 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
