HCSGD entry for TNP2
1. General information
| Official gene symbol | TNP2 |
|---|---|
| Entrez ID | 7142 |
| Gene full name | transition protein 2 (during histone to protamine replacement) |
| Other gene symbols | TP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000786 | Nucleosome | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0007339 | Binding of sperm to zona pellucida | IEA | biological_process |
| GO:0007340 | Acrosome reaction | IEA | biological_process |
| GO:0007341 | Penetration of zona pellucida | IEA | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0030317 | Sperm motility | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8456963565 | 0.7777901068 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0613585861 |
| GSE13712_SHEAR | Down | -0.0612286499 |
| GSE13712_STATIC | Down | -0.0273709163 |
| GSE19018 | Up | 0.0677607537 |
| GSE19899_A1 | Down | -0.0059172603 |
| GSE19899_A2 | Up | 0.0228374273 |
| PubMed_21979375_A1 | Up | 0.1330793411 |
| PubMed_21979375_A2 | Up | 0.0226042310 |
| GSE35957 | Up | 0.0044370130 |
| GSE36640 | Up | 0.0153406265 |
| GSE54402 | Down | -0.0078122845 |
| GSE9593 | Up | 0.0392019136 |
| GSE43922 | Up | 0.0512462980 |
| GSE24585 | Up | 0.0351152672 |
| GSE37065 | Down | -0.0716491506 |
| GSE28863_A1 | Down | -0.1710992696 |
| GSE28863_A2 | Down | -0.1804318494 |
| GSE28863_A3 | Up | 0.1003850213 |
| GSE28863_A4 | Up | 0.1155586823 |
| GSE48662 | Down | -0.0246377193 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029249 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
