HCSGD entry for TNP1

1. General information

Official gene symbolTNP1
Entrez ID7141
Gene full nametransition protein 1 (during histone to protamine replacement)
Other gene symbolsTP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000012Single strand break repairIDAbiological_process
GO:0000786NucleosomeIDAcellular_component
GO:0001673Male germ cell nucleusIEAcellular_component
GO:0003677DNA bindingIMPmolecular_function
GO:0006337Nucleosome disassemblyIMPbiological_process
GO:0006338Chromatin remodelingIDAbiological_process
GO:0006342Chromatin silencingIEPbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007286Spermatid developmentIDAbiological_process
GO:0007289Spermatid nucleus differentiationTASbiological_process
GO:0007290Spermatid nucleus elongationIMPbiological_process
GO:0019953Sexual reproductionIMPbiological_process
GO:0030317Sperm motilityIMPbiological_process
GO:0035042Fertilization, exchange of chromosomal proteinsTASbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00737693860.96931491200.22473194441.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2027404417
GSE13712_SHEARDown-0.3957911581
GSE13712_STATICUp0.0078452070
GSE19018Up0.0133497357
GSE19899_A1Up0.5207695241
GSE19899_A2Up2.1509079366
PubMed_21979375_A1Up3.6054209601
PubMed_21979375_A2Up1.0062616368
GSE35957Up0.0100290805
GSE36640Down-0.1720763757
GSE54402Up1.9006138526
GSE9593Up0.0243451585
GSE43922Up0.2801988030
GSE24585Up0.3317159651
GSE37065Down-0.0687817988
GSE28863_A1Down-0.0192595616
GSE28863_A2Up0.0583152943
GSE28863_A3Up0.2062780389
GSE28863_A4Up0.0807333229
GSE48662Down-0.0862905327

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-7-5pMIMAT0000252MIRT025822MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.