HCSGD entry for TNNI1
1. General information
| Official gene symbol | TNNI1 |
|---|---|
| Entrez ID | 7135 |
| Gene full name | troponin I type 1 (skeletal, slow) |
| Other gene symbols | SSTNI TNN1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005861 | Troponin complex | IEA | cellular_component |
| GO:0006942 | Regulation of striated muscle contraction | NAS | biological_process |
| GO:0030049 | Muscle filament sliding | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0055010 | Ventricular cardiac muscle tissue morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4823472702 | 0.8439034307 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2105609165 |
| GSE13712_SHEAR | Down | -0.1056472409 |
| GSE13712_STATIC | Up | 0.1321447190 |
| GSE19018 | Down | -0.0165881181 |
| GSE19899_A1 | Down | -0.0236147251 |
| GSE19899_A2 | Up | 0.0942455031 |
| PubMed_21979375_A1 | Up | 0.3238254538 |
| PubMed_21979375_A2 | Down | -0.1578184424 |
| GSE35957 | Up | 0.0327517550 |
| GSE36640 | Down | -0.0674975278 |
| GSE54402 | Up | 0.0502429117 |
| GSE9593 | Up | 0.0356691720 |
| GSE43922 | Up | 0.1013831478 |
| GSE24585 | Up | 0.0865361329 |
| GSE37065 | Up | 0.0190797085 |
| GSE28863_A1 | Down | -0.0149336590 |
| GSE28863_A2 | Up | 0.1345157444 |
| GSE28863_A3 | Up | 0.3476852414 |
| GSE28863_A4 | Up | 0.1952061914 |
| GSE48662 | Up | 0.0081905840 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016700 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT020440 | Microarray | Functional MTI (Weak) | 17242205 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT021876 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
