HCSGD entry for TNFAIP1

1. General information

Official gene symbolTNFAIP1
Entrez ID7126
Gene full nametumor necrosis factor, alpha-induced protein 1 (endothelial)
Other gene symbolsB12 B61 BTBD34 EDP1 hBACURD2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004842Ubiquitin-protein ligase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005768EndosomeIDAcellular_component
GO:0006260DNA replicationIEA ISSbiological_process
GO:0006915Apoptotic processTASbiological_process
GO:0006955Immune responseIEPbiological_process
GO:0009790Embryo developmentIEA ISSbiological_process
GO:0016477Cell migrationIMPbiological_process
GO:0016567Protein ubiquitinationIDAbiological_process
GO:0017049GTP-Rho bindingIDAmolecular_function
GO:0019904Protein domain specific bindingIEAmolecular_function
GO:0031463Cul3-RING ubiquitin ligase complexIDAcellular_component
GO:0035024Negative regulation of Rho protein signal transductionIMPbiological_process
GO:0043149Stress fiber assemblyIMPbiological_process
GO:0043161Proteasome-mediated ubiquitin-dependent protein catabolic processIDAbiological_process
GO:0045740Positive regulation of DNA replicationIEAbiological_process
GO:0051260Protein homooligomerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01922397330.91653345620.33785320431.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0508383019
GSE13712_SHEARUp0.3772258339
GSE13712_STATICUp0.3014199085
GSE19018Up0.5035689790
GSE19899_A1Up0.2177606291
GSE19899_A2Up1.4103056265
PubMed_21979375_A1Up0.5087992839
PubMed_21979375_A2Up1.1802062100
GSE35957Up0.4784064977
GSE36640Up0.5095842858
GSE54402Up0.1500433835
GSE9593Up0.2880683528
GSE43922Up0.4275974367
GSE24585Up0.1396447981
GSE37065Down-0.2874008189
GSE28863_A1Down-0.1510309829
GSE28863_A2Down-0.3081149830
GSE28863_A3Down-0.5890515253
GSE28863_A4Up0.0442433448
GSE48662Up0.0185901054

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-373-3pMIMAT0000726MIRT002521Microarray//Microarray;OtherFunctional MTI (Weak)15685193
hsa-miR-1296-5pMIMAT0005794MIRT036098CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT042325CLASHFunctional MTI (Weak)23622248
hsa-miR-17-5pMIMAT0000070MIRT051004CLASHFunctional MTI (Weak)23622248
hsa-let-7e-5pMIMAT0000066MIRT051605CLASHFunctional MTI (Weak)23622248
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-373-3pMIMAT0000726NAhsa-miR-37315685193
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.