HCSGD entry for TSPAN6


1. General information

Official gene symbolTSPAN6
Entrez ID7105
Gene full nametetraspanin 6
Other gene symbolsT245 TM4SF6 TSPAN-6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004871Signal transducer activityIMPmolecular_function
GO:0007165Signal transductionIMPbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0043123Positive regulation of I-kappaB kinase/NF-kappaB signalingIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.16559124270.48181917480.80504748801.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5594213254
GSE13712_SHEARDown-0.3508453224
GSE13712_STATICDown-0.4138872391
GSE19018Down-0.3105557715
GSE19899_A1Up0.3069374620
GSE19899_A2Down-0.4856006005
PubMed_21979375_A1Down-0.0635276107
PubMed_21979375_A2Up0.2228256278
GSE35957Up0.0616076569
GSE36640Up0.3777378467
GSE54402Down-0.1698893249
GSE9593Up0.6284719831
GSE43922Down-0.0231231020
GSE24585Up0.0843613047
GSE37065Up0.1954467199
GSE28863_A1Up0.1442784546
GSE28863_A2Up0.4512380961
GSE28863_A3Down-0.4924055356
GSE28863_A4Up0.0951994274
GSE48662Up0.0884992026

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-145-5pMIMAT0000437MIRT021536Reporter assay;MicroarrayFunctional MTI21351259
hsa-miR-142-3pMIMAT0000434MIRT021618MicroarrayFunctional MTI (Weak)17612493
hsa-miR-132-3pMIMAT0000426MIRT021861MicroarrayFunctional MTI (Weak)17612493
hsa-miR-128-3pMIMAT0000424MIRT021978MicroarrayFunctional MTI (Weak)17612493
hsa-miR-124-3pMIMAT0000422MIRT022561MicroarrayFunctional MTI (Weak)18668037
hsa-miR-484MIMAT0002174MIRT042158CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.