HCSGD entry for THBS4

1. General information

Official gene symbolTHBS4
Entrez ID7060
Gene full namethrombospondin 4
Other gene symbolsTSP4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001938Positive regulation of endothelial cell proliferationIDAbiological_process
GO:0005178Integrin bindingIDAmolecular_function
GO:0005509Calcium ion bindingIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEA TAScellular_component
GO:0005604Basement membraneIDAcellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005783Endoplasmic reticulumISScellular_component
GO:0006986Response to unfolded proteinIEAbiological_process
GO:0007155Cell adhesionIEAbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0008201Heparin bindingIDAmolecular_function
GO:0016525Negative regulation of angiogenesisIEPbiological_process
GO:0016529Sarcoplasmic reticulumISScellular_component
GO:0031012Extracellular matrixISScellular_component
GO:0034103Regulation of tissue remodelingISSbiological_process
GO:0034976Response to endoplasmic reticulum stressISSbiological_process
GO:0048266Behavioral response to painISSbiological_process
GO:0048771Tissue remodelingIEAbiological_process
GO:0050731Positive regulation of peptidyl-tyrosine phosphorylationIDAbiological_process
GO:0051451Myoblast migrationIDAbiological_process
GO:0051781Positive regulation of cell divisionIEAbiological_process
GO:0071603Endothelial cell-cell adhesionIDAbiological_process
GO:0090023Positive regulation of neutrophil chemotaxisIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.17489362870.28717415750.82100502941.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0037314528
GSE13712_SHEARDown-0.0888361881
GSE13712_STATICUp0.0113429497
GSE19018Down-0.1535115261
GSE19899_A1Down-0.0907641594
GSE19899_A2Up0.1812365248
PubMed_21979375_A1Down-0.1662302042
PubMed_21979375_A2Down-0.0444866721
GSE35957Down-0.3823572564
GSE36640Down-0.0951946336
GSE54402Down-0.2278658837
GSE9593Up0.1958499220
GSE43922Up0.0213315629
GSE24585Up0.6562445336
GSE37065Down-1.0773604438
GSE28863_A1Up1.7183259825
GSE28863_A2Up0.5063508559
GSE28863_A3Up0.1210729038
GSE28863_A4Down-0.0258214414
GSE48662Up0.0830922817

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.