HCSGD entry for THBS3
1. General information
| Official gene symbol | THBS3 |
|---|---|
| Entrez ID | 7059 |
| Gene full name | thrombospondin 3 |
| Other gene symbols | TSP3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003417 | Growth plate cartilage development | IEA | biological_process |
| GO:0005509 | Calcium ion binding | IEA NAS | molecular_function |
| GO:0005576 | Extracellular region | IEA TAS | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007160 | Cell-matrix adhesion | NAS | biological_process |
| GO:0008201 | Heparin binding | IDA IEA | molecular_function |
| GO:0043931 | Ossification involved in bone maturation | IEA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0060346 | Bone trabecula formation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4516705254 | 0.0381401163 | 0.9999902473 | 0.3679209447 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1511802758 |
| GSE13712_SHEAR | Down | -0.3543572927 |
| GSE13712_STATIC | Up | 0.0707826071 |
| GSE19018 | Up | 0.0204956182 |
| GSE19899_A1 | Down | -0.1290477774 |
| GSE19899_A2 | Down | -0.2515093627 |
| PubMed_21979375_A1 | Down | -1.6102063441 |
| PubMed_21979375_A2 | Down | -0.2412205099 |
| GSE35957 | Up | 0.1919899834 |
| GSE36640 | Up | 0.8473188043 |
| GSE54402 | Down | -0.2454357515 |
| GSE9593 | Up | 0.1120231949 |
| GSE43922 | Down | -0.8033341527 |
| GSE24585 | Up | 0.7483263197 |
| GSE37065 | Down | -0.4706861327 |
| GSE28863_A1 | Up | 0.1530025876 |
| GSE28863_A2 | Up | 0.5747870551 |
| GSE28863_A3 | Down | -0.5025098999 |
| GSE28863_A4 | Down | -0.1566567868 |
| GSE48662 | Up | 0.0026656085 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017421 | Microarray | Functional MTI (Weak) | 18185580 |
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