HCSGD entry for TCN1
1. General information
| Official gene symbol | TCN1 |
|---|---|
| Entrez ID | 6947 |
| Gene full name | transcobalamin I (vitamin B12 binding protein, R binder family) |
| Other gene symbols | TC-1 TC1 TCI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006824 | Cobalt ion transport | IEA | biological_process |
| GO:0009235 | Cobalamin metabolic process | IBA TAS | biological_process |
| GO:0015889 | Cobalamin transport | IEA | biological_process |
| GO:0031419 | Cobalamin binding | IBA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6202153414 | 0.7940593898 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0055216314 |
| GSE13712_SHEAR | Up | 0.0816817005 |
| GSE13712_STATIC | Up | 0.1148502533 |
| GSE19018 | Up | 0.0616852050 |
| GSE19899_A1 | Up | 0.2725142908 |
| GSE19899_A2 | Down | -0.0198107127 |
| PubMed_21979375_A1 | Up | 0.0055579757 |
| PubMed_21979375_A2 | Up | 0.1998286918 |
| GSE35957 | Up | 0.1324369186 |
| GSE36640 | Up | 0.0665308263 |
| GSE54402 | Up | 0.0085530596 |
| GSE9593 | Down | -0.0173126997 |
| GSE43922 | Up | 0.0088003665 |
| GSE24585 | Down | -0.1721267918 |
| GSE37065 | Down | -0.0134095009 |
| GSE28863_A1 | Down | -0.0596533368 |
| GSE28863_A2 | Down | -0.1853830380 |
| GSE28863_A3 | Up | 0.1314077055 |
| GSE28863_A4 | Down | -0.0184800921 |
| GSE48662 | Up | 0.0891891122 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Hydroxocobalamin | DB00200 | APRD01022 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029712 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
