HCSGD entry for MLX
1. General information
| Official gene symbol | MLX |
|---|---|
| Entrez ID | 6945 |
| Gene full name | MLX, MAX dimerization protein |
| Other gene symbols | MAD7 MXD7 TCFL4 bHLHd13 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | NAS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0006913 | Nucleocytoplasmic transport | IEA | biological_process |
| GO:0008134 | Transcription factor binding | IPI | molecular_function |
| GO:0031325 | Positive regulation of cellular metabolic process | TAS | biological_process |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IPI | molecular_function |
| GO:0046983 | Protein dimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5513001178 | 0.5001443448 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1092076362 |
| GSE13712_SHEAR | Down | -0.1419464978 |
| GSE13712_STATIC | Down | -0.1099360289 |
| GSE19018 | Down | -0.5222977095 |
| GSE19899_A1 | Up | 0.2637131396 |
| GSE19899_A2 | Up | 0.1374932250 |
| PubMed_21979375_A1 | Up | 0.2941421619 |
| PubMed_21979375_A2 | Up | 0.2498594374 |
| GSE35957 | Down | -0.0840748538 |
| GSE36640 | Down | -0.6935652059 |
| GSE54402 | Up | 0.2585592095 |
| GSE9593 | Up | 0.0918993193 |
| GSE43922 | Up | 0.1484474222 |
| GSE24585 | Up | 0.0409112675 |
| GSE37065 | Up | 0.0018641141 |
| GSE28863_A1 | Down | -0.2288615608 |
| GSE28863_A2 | Down | -0.2018066096 |
| GSE28863_A3 | Down | -0.1959727539 |
| GSE28863_A4 | Up | 0.0947266828 |
| GSE48662 | Up | 0.0347606690 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-33a-5p | MIMAT0000091 | MIRT028193 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-320b | MIMAT0005792 | MIRT036245 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041914 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043912 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044847 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045597 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-218-5p | MIMAT0000275 | MIRT046985 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049076 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
