HCSGD entry for TCEB2
1. General information
| Official gene symbol | TCEB2 |
|---|---|
| Entrez ID | 6923 |
| Gene full name | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) |
| Other gene symbols | ELOB SIII |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003746 | Translation elongation factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | TAS | biological_process |
| GO:0006461 | Protein complex assembly | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0031462 | Cul2-RING ubiquitin ligase complex | IDA | cellular_component |
| GO:0031466 | Cul5-RING ubiquitin ligase complex | IDA | cellular_component |
| GO:0031625 | Ubiquitin protein ligase binding | IDA | molecular_function |
| GO:0050434 | Positive regulation of viral transcription | TAS | biological_process |
| GO:0061418 | Regulation of transcription from RNA polymerase II promoter in response to hypoxia | TAS | biological_process |
| GO:0070449 | Elongin complex | IEA | cellular_component |
| GO:0071456 | Cellular response to hypoxia | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1521882261 | 0.8212621025 | 0.7787220645 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1276163710 |
| GSE13712_SHEAR | Down | -0.2001393455 |
| GSE13712_STATIC | Down | -0.1759369604 |
| GSE19018 | Up | 0.0228959682 |
| GSE19899_A1 | Up | 0.5295973870 |
| GSE19899_A2 | Up | 0.4634104194 |
| PubMed_21979375_A1 | Up | 0.6262208666 |
| PubMed_21979375_A2 | Up | 0.4774875266 |
| GSE35957 | Up | 0.1627120084 |
| GSE36640 | Up | 0.2702359494 |
| GSE54402 | Up | 0.1162729047 |
| GSE9593 | Up | 0.1348570979 |
| GSE43922 | Up | 0.2532823300 |
| GSE24585 | Down | -0.1798274853 |
| GSE37065 | Down | -0.3312155613 |
| GSE28863_A1 | Down | -0.2162102774 |
| GSE28863_A2 | Down | -0.2027247766 |
| GSE28863_A3 | Up | 0.0554763133 |
| GSE28863_A4 | Up | 0.0429884541 |
| GSE48662 | Up | 0.1258975525 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-125a-5p | MIMAT0000443 | MIRT021300 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-484 | MIMAT0002174 | MIRT041767 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046585 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049493 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
