HCSGD entry for TCEA2
1. General information
| Official gene symbol | TCEA2 |
|---|---|
| Entrez ID | 6919 |
| Gene full name | transcription elongation factor A (SII), 2 |
| Other gene symbols | TFIIS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003746 | Translation elongation factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006354 | DNA-templated transcription, elongation | NAS | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0008023 | Transcription elongation factor complex | NAS | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0032784 | Regulation of DNA-templated transcription, elongation | IEA NAS | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8067234869 | 0.2105457429 | 0.9999902473 | 0.8862181804 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1453485327 |
| GSE13712_SHEAR | Down | -0.4898536047 |
| GSE13712_STATIC | Down | -0.3487494345 |
| GSE19018 | Up | 0.0548997812 |
| GSE19899_A1 | Down | -0.2935128817 |
| GSE19899_A2 | Down | -0.3690032126 |
| PubMed_21979375_A1 | Up | 0.1029322493 |
| PubMed_21979375_A2 | Up | 0.1786988569 |
| GSE35957 | Down | -0.0471575287 |
| GSE36640 | Up | 0.4100565464 |
| GSE54402 | Down | -0.1614312220 |
| GSE9593 | Up | 0.3705181039 |
| GSE43922 | Down | -0.3587563765 |
| GSE24585 | Up | 0.0881078169 |
| GSE37065 | Down | -0.1551919855 |
| GSE28863_A1 | Down | -0.1319322024 |
| GSE28863_A2 | Down | -0.2335655098 |
| GSE28863_A3 | Down | -0.1962856879 |
| GSE28863_A4 | Up | 0.0858677327 |
| GSE48662 | Up | 0.1828025210 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-18a-5p | MIMAT0000072 | MIRT050731 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT051001 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
