HCSGD entry for TBXAS1
1. General information
| Official gene symbol | TBXAS1 |
|---|---|
| Entrez ID | 6916 |
| Gene full name | thromboxane A synthase 1 (platelet) |
| Other gene symbols | BDPLT14 CYP5 CYP5A1 GHOSAL THAS TS TXAS TXS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004497 | Monooxygenase activity | IEA | molecular_function |
| GO:0004796 | Thromboxane-A synthase activity | IEA | molecular_function |
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006690 | Icosanoid metabolic process | TAS | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016705 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | IEA | molecular_function |
| GO:0019369 | Arachidonic acid metabolic process | TAS | biological_process |
| GO:0019371 | Cyclooxygenase pathway | TAS | biological_process |
| GO:0020037 | Heme binding | IEA | molecular_function |
| GO:0030644 | Cellular chloride ion homeostasis | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045907 | Positive regulation of vasoconstriction | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0077999430 | 0.9886184605 | 0.2286217149 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0029739025 |
| GSE13712_SHEAR | Up | 0.1380784477 |
| GSE13712_STATIC | Up | 0.0651643951 |
| GSE19018 | Down | -0.0907814608 |
| GSE19899_A1 | Up | 0.3262281313 |
| GSE19899_A2 | Up | 0.4464065466 |
| PubMed_21979375_A1 | Up | 0.0756677014 |
| PubMed_21979375_A2 | Up | 0.8779928668 |
| GSE35957 | Up | 0.0201923802 |
| GSE36640 | Up | 2.7985201245 |
| GSE54402 | Up | 0.7243002859 |
| GSE9593 | Up | 0.0835588006 |
| GSE43922 | Up | 0.7465754560 |
| GSE24585 | Down | -0.0972369178 |
| GSE37065 | Up | 0.2080980503 |
| GSE28863_A1 | Down | -0.0828811059 |
| GSE28863_A2 | Up | 0.1211213222 |
| GSE28863_A3 | Up | 0.1391859719 |
| GSE28863_A4 | Up | 0.0430723777 |
| GSE48662 | Up | 1.6147972010 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017567 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
