HCSGD entry for TBXA2R
1. General information
| Official gene symbol | TBXA2R |
|---|---|
| Entrez ID | 6915 |
| Gene full name | thromboxane A2 receptor |
| Other gene symbols | BDPLT13 TXA2-R |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001669 | Acrosomal vesicle | IEA | cellular_component |
| GO:0004960 | Thromboxane receptor activity | IEA | molecular_function |
| GO:0004961 | Thromboxane A2 receptor activity | TAS | molecular_function |
| GO:0005085 | Guanyl-nucleotide exchange factor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006954 | Inflammatory response | IEA | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007204 | Positive regulation of cytosolic calcium ion concentration | IEA | biological_process |
| GO:0007584 | Response to nutrient | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019932 | Second-messenger-mediated signaling | IEA | biological_process |
| GO:0030168 | Platelet activation | TAS | biological_process |
| GO:0032496 | Response to lipopolysaccharide | IEA | biological_process |
| GO:0038193 | Thromboxane A2 signaling pathway | TAS | biological_process |
| GO:0042493 | Response to drug | IEA | biological_process |
| GO:0043087 | Regulation of GTPase activity | TAS | biological_process |
| GO:0045766 | Positive regulation of angiogenesis | IEA | biological_process |
| GO:0045777 | Positive regulation of blood pressure | IEA | biological_process |
| GO:0045907 | Positive regulation of vasoconstriction | IEA | biological_process |
| GO:0045987 | Positive regulation of smooth muscle contraction | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6579664109 | 0.3416055013 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1543883092 |
| GSE13712_SHEAR | Up | 0.0764532410 |
| GSE13712_STATIC | Up | 0.0840763610 |
| GSE19018 | Down | -0.1680952323 |
| GSE19899_A1 | Down | -0.0813430317 |
| GSE19899_A2 | Down | -0.0689610354 |
| PubMed_21979375_A1 | Down | -0.3266038087 |
| PubMed_21979375_A2 | Down | -0.4589059149 |
| GSE35957 | Up | 0.0850454800 |
| GSE36640 | Up | 0.8148715564 |
| GSE54402 | Down | -0.0518213839 |
| GSE9593 | Up | 0.0051535623 |
| GSE43922 | Down | -0.2091858227 |
| GSE24585 | Up | 0.1265517427 |
| GSE37065 | Down | -0.0863540074 |
| GSE28863_A1 | Down | -0.1260534634 |
| GSE28863_A2 | Up | 0.0231789314 |
| GSE28863_A3 | Up | 0.1942972487 |
| GSE28863_A4 | Up | 0.0629841594 |
| GSE48662 | Up | 0.2835835320 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Ridogrel | DB01207 | APRD00271 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022135 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
