HCSGD entry for TBX6

1. General information

Official gene symbolTBX6
Entrez ID6911
Gene full nameT-box 6
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0001085RNA polymerase II transcription factor bindingISSmolecular_function
GO:0001102RNA polymerase II activating transcription factor bindingISSmolecular_function
GO:0001191RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcriptionISSmolecular_function
GO:0001707Mesoderm formationIEAbiological_process
GO:0001708Cell fate specificationIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006366Transcription from RNA polymerase II promoterISSbiological_process
GO:0007498Mesoderm developmentTASbiological_process
GO:0009653Anatomical structure morphogenesisTASbiological_process
GO:0023019Signal transduction involved in regulation of gene expressionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67842060330.73822648460.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1207936677
GSE13712_SHEARDown-0.2121632001
GSE13712_STATICDown-0.1871069568
GSE19018Up0.1603188132
GSE19899_A1Up0.0084214263
GSE19899_A2Up0.0172113991
PubMed_21979375_A1Up0.2593899595
PubMed_21979375_A2Down-0.0092728414
GSE35957Up0.0994021630
GSE36640Up0.0455105714
GSE54402Down-0.1126899510
GSE9593Up0.0837458192
GSE43922Up0.0297871814
GSE24585Up0.2375915870
GSE37065Down-0.0609793608
GSE28863_A1Down-0.1211764958
GSE28863_A2Down-0.2285695891
GSE28863_A3Up0.3436409892
GSE28863_A4Up0.0888969592
GSE48662Up0.1391142387

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.