HCSGD entry for TBL1X
1. General information
| Official gene symbol | TBL1X |
|---|---|
| Entrez ID | 6907 |
| Gene full name | transducin (beta)-like 1X-linked |
| Other gene symbols | EBI SMAP55 TBL1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000118 | Histone deacetylase complex | IDA | cellular_component |
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0003714 | Transcription corepressor activity | IDA IGI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005876 | Spindle microtubule | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006508 | Proteolysis | IMP | biological_process |
| GO:0007219 | Notch signaling pathway | TAS | biological_process |
| GO:0007605 | Sensory perception of sound | IMP | biological_process |
| GO:0008013 | Beta-catenin binding | IPI | molecular_function |
| GO:0008022 | Protein C-terminus binding | IPI | molecular_function |
| GO:0008134 | Transcription factor binding | IPI | molecular_function |
| GO:0017053 | Transcriptional repressor complex | IDA | cellular_component |
| GO:0019904 | Protein domain specific binding | IPI | molecular_function |
| GO:0042393 | Histone binding | IDA | molecular_function |
| GO:0043161 | Proteasome-mediated ubiquitin-dependent protein catabolic process | ISS | biological_process |
| GO:0044212 | Transcription regulatory region DNA binding | IDA | molecular_function |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0060070 | Canonical Wnt signaling pathway | IMP | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9605429087 | 0.0221983321 | 0.9999902473 | 0.2864271659 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2363041664 |
| GSE13712_SHEAR | Down | -0.5356751893 |
| GSE13712_STATIC | Down | -0.3261617102 |
| GSE19018 | Up | 0.0900953383 |
| GSE19899_A1 | Down | -0.1693465398 |
| GSE19899_A2 | Down | -0.0009596561 |
| PubMed_21979375_A1 | Up | 0.0688727074 |
| PubMed_21979375_A2 | Up | 0.4875883537 |
| GSE35957 | Down | -0.5176919480 |
| GSE36640 | Down | -0.6105880964 |
| GSE54402 | Down | -0.2967488083 |
| GSE9593 | Down | -0.2280733666 |
| GSE43922 | Up | 0.0019376503 |
| GSE24585 | Down | -1.4570538715 |
| GSE37065 | Down | -0.1941341873 |
| GSE28863_A1 | Up | 0.0393295976 |
| GSE28863_A2 | Down | -0.0713423085 |
| GSE28863_A3 | Up | 0.0701953679 |
| GSE28863_A4 | Down | -0.0011504826 |
| GSE48662 | Up | 0.0797727467 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019134 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024299 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026920 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049369 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
