HCSGD entry for TBCD

1. General information

Official gene symbolTBCD
Entrez ID6904
Gene full nametubulin folding cofactor D
Other gene symbolsSSD-1 tfcD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005096GTPase activator activityIDA IMPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005874MicrotubuleTAScellular_component
GO:0005912Adherens junctionISScellular_component
GO:0005923Tight junctionISScellular_component
GO:0006457Protein foldingIDA TASbiological_process
GO:0007023Post-chaperonin tubulin folding pathwayIDAbiological_process
GO:0010812Negative regulation of cell-substrate adhesionISSbiological_process
GO:0016328Lateral plasma membraneISScellular_component
GO:0031115Negative regulation of microtubule polymerizationIDAbiological_process
GO:0034333Adherens junction assemblyISSbiological_process
GO:0043085Positive regulation of catalytic activityIDA IMPbiological_process
GO:0043547Positive regulation of GTPase activityIDA IMPbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0048487Beta-tubulin bindingIDAmolecular_function
GO:0050790Regulation of catalytic activityIDA IMPbiological_process
GO:0051084'de novo' posttranslational protein foldingTASbiological_process
GO:0051087Chaperone bindingTASmolecular_function
GO:0070830Tight junction assemblyISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86998937730.45572104020.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0487057780
GSE13712_SHEARUp0.1551998034
GSE13712_STATICUp0.0562476444
GSE19018Up0.0459219050
GSE19899_A1Down-0.1534408679
GSE19899_A2Down-0.1012889506
PubMed_21979375_A1Down-0.1370341692
PubMed_21979375_A2Down-0.0438660226
GSE35957Up0.0421076838
GSE36640Down-0.1839142188
GSE54402Down-0.0922252956
GSE9593Up0.0554954508
GSE43922Down-0.2069536037
GSE24585Up0.5065854210
GSE37065Down-0.2286569802
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0775242596

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT024063ProteomicsFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.