HCSGD entry for TARS
1. General information
| Official gene symbol | TARS |
|---|---|
| Entrez ID | 6897 |
| Gene full name | threonyl-tRNA synthetase |
| Other gene symbols | ThrRS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004829 | Threonine-tRNA ligase activity | IEA NAS TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA IEA NAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006412 | Translation | NAS | biological_process |
| GO:0006418 | TRNA aminoacylation for protein translation | TAS | biological_process |
| GO:0006435 | Threonyl-tRNA aminoacylation | IEA NAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0042803 | Protein homodimerization activity | NAS | molecular_function |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2751957486 | 0.6307618707 | 0.9712291901 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0183086200 |
| GSE13712_SHEAR | Up | 0.2554693313 |
| GSE13712_STATIC | Up | 0.0278576143 |
| GSE19018 | Up | 0.1591682324 |
| GSE19899_A1 | Up | 0.3325264721 |
| GSE19899_A2 | Up | 0.1193176984 |
| PubMed_21979375_A1 | Up | 1.0291905059 |
| PubMed_21979375_A2 | Up | 0.1659193926 |
| GSE35957 | Down | -0.4367781724 |
| GSE36640 | Down | -0.2566024052 |
| GSE54402 | Up | 0.2271755606 |
| GSE9593 | Up | 0.0253904443 |
| GSE43922 | Up | 0.4949308943 |
| GSE24585 | Down | -0.0345255195 |
| GSE37065 | Down | -0.2580327378 |
| GSE28863_A1 | Down | -0.1274955243 |
| GSE28863_A2 | Down | -0.0664677292 |
| GSE28863_A3 | Down | -0.5365592617 |
| GSE28863_A4 | Down | -0.1976776331 |
| GSE48662 | Up | 0.1782952075 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Threonine | DB00156 | NUTR00057 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-3p | MIMAT0004950 | MIRT037167 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-191-5p | MIMAT0000440 | MIRT045807 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052487 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
