HCSGD entry for TAPBP

1. General information

Official gene symbolTAPBP
Entrez ID6892
Gene full nameTAP binding protein (tapasin)
Other gene symbolsNGS17 TAPA TPN TPSN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIDAcellular_component
GO:0002397MHC class I protein complex assemblyIEAbiological_process
GO:0002474Antigen processing and presentation of peptide antigen via MHC class ITASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumTAScellular_component
GO:0005789Endoplasmic reticulum membraneIDAcellular_component
GO:0006200ATP catabolic processTASbiological_process
GO:0006461Protein complex assemblyTASbiological_process
GO:0006890Retrograde vesicle-mediated transport, Golgi to ERNASbiological_process
GO:0006952Defense responseIEAbiological_process
GO:0006955Immune responseTASbiological_process
GO:0015433Peptide antigen-transporting ATPase activityTASmolecular_function
GO:0015833Peptide transportTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneTAScellular_component
GO:0019885Antigen processing and presentation of endogenous peptide antigen via MHC class IIEAbiological_process
GO:0042288MHC class I protein bindingTASmolecular_function
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0042605Peptide antigen bindingTASmolecular_function
GO:0042824MHC class I peptide loading complexNAScellular_component
GO:0042825TAP complexIDAcellular_component
GO:0042886Amide transportTASbiological_process
GO:0046978TAP1 bindingIPI TASmolecular_function
GO:0046979TAP2 bindingIPI TASmolecular_function
GO:0050823Peptide antigen stabilizationISSbiological_process
GO:0051082Unfolded protein bindingTASmolecular_function
GO:0055085Transmembrane transportTASbiological_process
GO:0071556Integral component of lumenal side of endoplasmic reticulum membraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01741229820.89112021200.32458151561.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0014714287
GSE13712_SHEARUp0.4752484411
GSE13712_STATICUp0.2768226451
GSE19018Down-0.2756637284
GSE19899_A1Down-0.1039553617
GSE19899_A2Up0.7892356037
PubMed_21979375_A1Up0.7374656750
PubMed_21979375_A2Up0.4886515836
GSE35957Down-0.3748777044
GSE36640Up0.6488571889
GSE54402Down-0.0052040336
GSE9593Up0.2855208178
GSE43922Down-0.0791941604
GSE24585Up0.4453496018
GSE37065Up0.4208355153
GSE28863_A1Up1.1473208635
GSE28863_A2Up1.1633265718
GSE28863_A3Down-0.2077475243
GSE28863_A4Down-0.2306678421
GSE48662Up0.1984203531

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-7-5pMIMAT0000252MIRT025665MicroarrayFunctional MTI (Weak)19073608
hsa-miR-30a-5pMIMAT0000087MIRT028631ProteomicsFunctional MTI (Weak)18668040
hsa-miR-744-5pMIMAT0004945MIRT037630CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-3pMIMAT0002891MIRT040821CLASHFunctional MTI (Weak)23622248
hsa-miR-324-3pMIMAT0000762MIRT042996CLASHFunctional MTI (Weak)23622248
hsa-miR-100-5pMIMAT0000098MIRT048442CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.