HCSGD entry for KLF5
1. General information
| Official gene symbol | KLF5 |
|---|---|
| Entrez ID | 688 |
| Gene full name | Kruppel-like factor 5 (intestinal) |
| Other gene symbols | BTEB2 CKLF IKLF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IEA | biological_process |
| GO:0030033 | Microvillus assembly | IEA | biological_process |
| GO:0035914 | Skeletal muscle cell differentiation | IEA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0071407 | Cellular response to organic cyclic compound | IEA | biological_process |
| GO:1901653 | Cellular response to peptide | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0230517496 | 0.5676483302 | 0.3616227976 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2008770510 |
| GSE13712_SHEAR | Up | 0.3908836180 |
| GSE13712_STATIC | Up | 0.0758961432 |
| GSE19018 | Up | 0.2923237895 |
| GSE19899_A1 | Up | 0.4454010500 |
| GSE19899_A2 | Up | 0.3168997168 |
| PubMed_21979375_A1 | Up | 1.2415511163 |
| PubMed_21979375_A2 | Up | 0.8041825202 |
| GSE35957 | Up | 1.4323462758 |
| GSE36640 | Up | 0.3009002355 |
| GSE54402 | Down | -0.1594276764 |
| GSE9593 | Up | 0.5559923793 |
| GSE43922 | Up | 0.2124790474 |
| GSE24585 | Up | 0.3536565953 |
| GSE37065 | Up | 0.1502798520 |
| GSE28863_A1 | Down | -0.9424749122 |
| GSE28863_A2 | Up | 0.0542390837 |
| GSE28863_A3 | Down | -0.1360306379 |
| GSE28863_A4 | Down | -0.1480255834 |
| GSE48662 | Down | -0.6196078602 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-141-3p | MIMAT0000432 | MIRT001812 | Luciferase reporter assay//Reporter assay;Other | Non-Functional MTI | 15131085 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021472 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT022040 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030940 | Microarray | Functional MTI (Weak) | 18591254 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
